International Chemical Safety Cards XYLIDINE (MIXED ISOMERS) ICSC: 0600 Dimethylaniline Aminodimethylbenzene Dimethylphenylamine C8H11N / (CH3)2C6H3NH2 Molecular mass: 121.2 ICSC #    0600 CAS #     1300-73-8 RTECS # ZE8575000 UN #        1711 EC #         612-027-00-0 April 19, 2007 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Water spray, carbon dioxide , foam , powder . EXPLOSION Above 90-98°C explosive vapour/air mixtures may be formed. Above 90-98°C use a closed system, ventilation. EXPOSURE AVOID ALL CONTACT!  •INHALATION Dizziness. Drowsiness. Headache. Nausea. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN MAY BE ABSORBED! (See Ingestion) Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Safety spectacles or eye protection in combination with breathing protection. Rinse with plenty of water (remove contact lenses if easily possible).  •INGESTION Blue lips or fingernails. Blue skin. Dizziness. Drowsiness. Headache. Nausea. Unconsciousness. Do not eat, drink, or smoke during work. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Chemical protection suit. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Separated from strong oxidants, acids, acid anhydrides, acid chlorides, hypochlorites, halogens, food and feedstuffs . Well closed. Store in an area without drain or sewer access. Do not transport with food and feedstuffs. Note: C T symbol N symbol R: 23/24/25-33-51/53 S: 1/2-28-36/37-45-61 UN Hazard Class: 6.1 UN Packing Group: II Signal: Warning Excl mark-Health haz Combustible liquid Harmful if swallowed Harmful in contact with skin Suspected of causing cancer May cause drowsiness or dizziness May cause damage to blood May cause damage to blood, liver and kidneys through prolonged or repeated exposure SEE IMPORTANT INFORMATION ON BACK ICSC: 0600 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards XYLIDINE (MIXED ISOMERS) ICSC: 0600 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: PALE YELLOWTO BROWN LIQUID , WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic and corrosive fumes including nitrogen oxides . Reacts violently with strong oxidants. Reacts with hypochlorites forming explosive chloroamines. Reacts with acids , acid anhydrides , acid chlorides and halogens . Attacks plastic and rubber. OCCUPATIONAL EXPOSURE LIMITS: TLV: (Inhalable fraction) and (vapour) 0.5 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2006). MAK: skin absorption (H); Carcinogen category: 3A; (DFG 2006). OSHA PEL†: TWA 5 ppm (25 mg/m3) skin NIOSH REL: TWA 2 ppm (10 mg/m3) skin NIOSH IDLH: 50 ppm See: 1300738 ROUTES OF EXPOSURE: The substance can be absorbed into the body in hazardous amounts by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. EFFECTS OF SHORT-TERM EXPOSURE: Exposure at high levels could cause lowering of consciousness. Exposure at high levels may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the blood , resulting in anaemia . The substance may have effects on the kidneys and liver . This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: 216-228°C Relative density (water = 1): 0.97-1.07 Solubility in water, g/100 ml at 20°C: 0.4 - 15 Vapour pressure, Pa at 20°C: 4-130 Relative vapour density (air = 1): 4.2 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flash point: 90-98°C c.c. Auto-ignition temperature: 520-590°C Explosive limits, vol% in air: 1-7 Octanol/water partition coefficient as log Pow: 1.8- 2.2 (estimated) ENVIRONMENTAL DATA This substance may be hazardous in the environment; special attention should be given to aquatic organisms. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Commercial xylidine is a mixture of isomers where the 2,4-, 2,5- and 2,6-isomers dominate. See also ICSC 1519 (2,6-Xylidine), 1562 (2,4-Xylidine), 0453 (3,4-Xylidine), 1686 (2,5-Xylidine), 1687 (3,5-Xylidine). Transport Emergency Card: TEC (R)-61S1711-L NFPA Code: H3; F1; R0 ADDITIONAL INFORMATION ICSC: 0600 XYLIDINE (MIXED ISOMERS) (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.