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beta-PROPIOLACTONE

ICSC: 0555

1,3-Propiolactone
2-Oxetanone
Propanolide
C3H4O2
Molecular mass: 72.06
ICSC #    0555
CAS #     57-57-8
RTECS # RQ7350000
UN #        2810
EC #         606-031-00-1
July 10, 1997 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Above 74°C explosive vapour/air mixtures may be formed.
Above 74°C use a closed system, ventilation.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
AVOID ALL CONTACT!

 •INHALATION Burning sensation. Cough. Headache. Nausea. Shortness of breath. Vomiting.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
 •SKIN Skin burns. Blisters.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
 •EYES Redness. Pain. Severe deep burns.
Face shield, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION Burning sensation. Sore throat. (See Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. (Extra personal protection: complete protective clothing including self-contained breathing apparatus).
Separated from food and feedstuffs . Cooled. Well closed. Ventilation along the floor.
Do not transport with food and feedstuffs.
Note: E
T+ symbol
R: 45-26-36/38
S: 53-45
UN Hazard Class: 6.1
UN Packing Group: I
ICSC: 0555 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

beta-PROPIOLACTONE

ICSC: 0555

I

M

P

O

R

T

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D

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A

PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH PUNGENT ODOUR.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance may polymerize due to warming with fire or explosion hazard.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.5 ppm; 1.5 mg/m3 A3 (ACGIH 1997).
MAK: skin absorption (H);
Carcinogen category: 2
(DFG 2006).
OSHA PEL: 1910.1013 See Appendix B
NIOSH REL: Ca See Appendix A
NIOSH IDLH: Ca N.D See: IDLH INDEX


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:


EFFECTS OF SHORT-TERM EXPOSURE:
The substance is corrosive to the eyes and irritates, the skin and the respiratory tract.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
This substance is probably carcinogenic to humans.

PHYSICAL
PROPERTIES

Boiling point (decomposes): 155°C
Melting point: -33.4°C
Relative density (water = 1): 1.1
Solubility in water, g/100 ml: 37
Vapour pressure, kPa at 25°C: 0.3
Flash point: 74°C
Explosive limits, vol% in air: 2.9-?

ENVIRONMENTAL
DATA


N O T E S

NFPA Code: H0; F2; R0;
Card has been partially updated in August 2007: see Occupational Exposure Limits.

ADDITIONAL INFORMATION



ICSC: 0555 beta-PROPIOLACTONE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
 
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