International Chemical Safety Cards

NICOTINE TARTRATE ICSC: 0521
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
Nicotine acid tartrate
Nicotine bitartrate
C10H14N2 • 2C4H6O6
Molecular mass: 462.5
6 Poison placard ICSC #    0521
CAS #     65-31-6
RTECS # QT0350000
UN #        1659
EC #         614-002-00-X
September 04, 1997 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST! AVOID EXPOSURE OF (PREGNANT) WOMEN!
IN ALL CASES CONSULT A DOCTOR!
 •INHALATION Nausea. Vomiting. Abdominal pain. Headache. Convulsions.
Ventilation (not if powder), local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
 •SKIN MAY BE ABSORBED! Redness. Pain. (See Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
 •EYES Pain. Redness.
Face shield, or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION (See Inhalation).
Do not eat, drink, or smoke during work.
Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Do NOT wash away into sewer. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting, then remove to safe place. (Extra personal protection: complete protective clothing including self-contained breathing apparatus).
Provision to contain effluent from fire extinguishing. Separated from strong oxidants, food and feedstuffs.
Do not transport with food and feedstuffs.
Note: A
T+ symbol
N symbol
R: 26/27/28-51/53
S: 1/2-13-28-45-61
UN Hazard Class: 6.1
UN Packing Group: II
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0521 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

NICOTINE TARTRATE ICSC: 0521
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PHYSICAL STATE; APPEARANCE:
WHITE FLAKES.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes of nitrogen oxides and carbon monoxide. Reacts violently with strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes and the skin. The substance may cause effects on the central nervous system , resulting in convulsions and respiratory failure. Exposure at high concentrations may result in death. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Animal tests show that this substance possibly causes toxic effects upon human reproduction.
PHYSICAL
PROPERTIES
Melting point: 90°C
Solubility in water: very good
Auto-ignition temperature: 244°C
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is toxic to aquatic organisms.
N O T E S
Transport Emergency Card: TEC (R)-61G67
Card has been partially updated in August 2007: see EU Classification.
ADDITIONAL INFORMATION


ICSC: 0521 NICOTINE TARTRATE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.