International Chemical Safety Cards 3,3'-DICHLOROBENZIDINE ICSC: 0481 3,3'-Dichlorobiphenyl-4,4'-ylenediamine 4,4'-Diamino-3,3'-dichlorobiphenyl C6H3ClNH2C6H3ClNH2/C12H10Cl2N2 Molecular mass: 253.1 ICSC #    0481 CAS #     91-94-1 RTECS # DD0525000 EC #         612-068-00-4 May 05, 2010 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Fine water spray, Dry powder. Carbon dioxide. EXPLOSION EXPOSURE See EFFECTS OF LONG-TERM OR REPEATED EXPOSURE. PREVENT DISPERSION OF DUST! STRICT HYGIENE!  •INHALATION Cough. Sore throat. Avoid inhalation of dust Local exhaust or breathing protection. Fresh air, rest. Seek medical attention if you feel unwell .  •SKIN MAY BE ABSORBED! Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell .  •EYES Face shield or eye protection in combination with breathing protection if powder. Rinse with plenty of water (remove contact lenses if easily possible).  •INGESTION Do not eat, drink, or smoke during work. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment . Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. ase sealable deleted and replaced by 21223060 in update May 2010 Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Store in original container. Store in an area without drain or sewer access. replaced by 22211100 in update May 2010 Do not transport with food and feedstuffs. Note: E T symbol N symbol R: 45-21-43-50/53 S: 53-45-60-61 Signal: Danger Excl mark-Health haz-Enviro Suspected of causing genetic defects May cause cancer May cause respiratory irritation May cause damage to liver through prolonged or repeated exposure if swallowed Toxic to aquatic life with long-lasting effects SEE IMPORTANT INFORMATION ON BACK ICSC: 0481 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 3,3'-DICHLOROBENZIDINE ICSC: 0481 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: GREY TO PURPLE CRYSTALS. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic and corrosive fumes including nitrogen oxides and hydrogen chloride . update may 2010 and replaced by 13347000 according to the CG OCCUPATIONAL EXPOSURE LIMITS: TLV: (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2009). MAK: skin absorption (H); Carcinogen category: 2 (DFG 2009). OSHA PEL: 1910.1007 See Appendix B NIOSH REL: Ca See Appendix A NIOSH IDLH: Ca N.D. See: IDLH INDEX ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. ion in the list of OELs mouse = 488 mg/kg bw (according to IUCLID) INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the respiratory tract. update May 2010 and replaced by 13709030 EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver. This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: 368°C Melting point: 132-133°C Solubility in water: (none) Auto-ignition temperature: 350°C Octanol/water partition coefficient as log Pow: 3.51 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment. It is strongly advised that this substance does not enter the environment. 0 added N O T E S The substance is combustible but no flash point is available in literature. Curithane C126 is a trade name. ADDITIONAL INFORMATION ICSC: 0481 3,3'-DICHLOROBENZIDINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.