International Chemical Safety Cards

DIISOPROPYLAMINE

ICSC: 0449

DIPA
N-(1-Methylethyl)-2-propanamine
C₆H₁₅N / CH₃CH(CH₃)NHCH(CH₃)CH₃
Molecular mass: 101.2

ICSC #    0449
CAS #     108-18-9
RTECS # IM4025000
UN #        1158
EC #         612-129-00-5
July 04, 1997 Validated

TYPES OF HAZARD/ EXPOSURE	ACUTE HAZARDS/ SYMPTOMS	PREVENTION	FIRST AID/ FIRE FIGHTING
FIRE	Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames, NO sparks, and NO smoking. NO contact with oxidants.	Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION	Vapour/air mixtures are explosive.	Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding).	In case of fire: keep drums, etc., cool by spraying with water.

EXPOSURE		PREVENT GENERATION OF MISTS! STRICT HYGIENE!
•INHALATION	Burning sensation. Cough. Headache. Nausea. Shortness of breath. Symptoms may be delayed (see Notes).	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
•SKIN	MAY BE ABSORBED! Pain. Blisters.	Protective clothing.	First rinse with plenty of water, then remove contaminated clothes and rinse again. Refer for medical attention.
•EYES	Redness. Pain. Blurred vision. Severe deep burns.	Safety spectacles, or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION	Abdominal cramps. Burning sensation. Nausea. Shock or collapse. Sore throat.	Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Wash away remainder with plenty of water. Personal protection: complete protective clothing including self-contained breathing apparatus.

Separated from strong oxidants, strong acids. Cool. Well closed. Keep in a well-ventilated room.

F symbol
C symbol
R: 11-20/22-34
S: 1/2-16-26-36/37/39-45
UN Hazard Class: 3
UN Subsidiary Risks: 8
UN Packing Group: II

SEE IMPORTANT INFORMATION ON BACK

ICSC: 0449

Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

DIISOPROPYLAMINE

ICSC: 0449

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PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes of nitrogen oxides. The substance is a strong base, it reacts violently with acid and is corrosive to copper and zinc and their alloys, aluminium and galvanized steel. Reacts violently with oxidants causing fire and explosion hazard. Attacks some forms of plastics.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 5 ppm as TWA; (skin); (ACGIH 2004).
OSHA PEL: TWA 5 ppm (20 mg/m³) skin
NIOSH REL: TWA 5 ppm (20 mg/m³) skin
NIOSH IDLH: 200 ppm See: 108189

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
Tear drawing. The vapour is corrosive to the eyes and the respiratory tract. Inhalation of the vapour may cause lung oedema (see Notes). Contact of the eyes with the vapour or liquid may induce visual disturbances. Exposure may result in death. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact with skin may cause dermatitis.

PHYSICAL
PROPERTIES

Boiling point: 84°C
Melting point: (see Notes) -61°C
Relative density (water = 1): 0.72
Solubility in water:
none
Vapour pressure, kPa at 20°C: 9.3

Relative vapour density (air = 1): 3.5
Flash point: -6°C o.c.
Auto-ignition temperature: 316°C
Explosive limits, vol% in air: 0.8-7.1
Octanol/water partition coefficient as log Pow: 1.64

ENVIRONMENTAL
DATA

The substance is harmful to aquatic organisms.

N O T E S

Other reported melting points: -91°C and -96°C. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. Card has been partly updated in October 2004. See sections Occupational Exposure Limits, EU classification, Emergency Response.

Transport Emergency Card: TEC (R)-30GFC-II

NFPA Code: H3; F3; R0;

ADDITIONAL INFORMATION

ICSC: 0449	DIISOPROPYLAMINE
(C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE:

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.