International Chemical Safety Cards

TRIMELLITIC ANHYDRIDE ICSC: 0345
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
1,2,4-Benzenetricarboxylic anhydride
1,3-Dihydro-1,3-dioxo-5-isobenzofurancarboxylic acid
C9H4O5
Molecular mass: 192.2
ICSC #    0345
CAS #     552-30-7
RTECS # DC2050000
EC #         607-097-00-4
April 22, 1994 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray, powder.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent build-up of electrostatic charges (e.g., by grounding). Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST! STRICT HYGIENE!

 •INHALATION Cough. Headache. Nausea. Shortness of breath. Wheezing. Symptoms may be delayed (see Notes).
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
 •SKIN Redness.
Protective gloves.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
 •EYES Redness. Pain.
Safety goggles or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION
Do not eat, drink, or smoke during work.
Rinse mouth. Give plenty of water to drink. Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder. Personal protection: P3 filter respirator for toxic particles.
Separated from strong oxidants. Dry.

Xn symbol
R: 37-41-42/43
S: 2-22-26-36/37/39
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0345 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

TRIMELLITIC ANHYDRIDE ICSC: 0345
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PHYSICAL STATE; APPEARANCE:
COLOURLESS CRYSTALS OR POWDER

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc.

CHEMICAL DANGERS:
Reacts violently with oxidants. Reacts slowly with water to form trimellitic acid.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.04 mg/m (Ceiling value) (ACGIH 2005).
MAK: 0.04 mg/m sensitization of respiratory tract (Sa);
Peak limitation category: I (1)
(DFG 2005).
OSHA PEL: none
NIOSH REL: TWA 0.005 ppm (0.04 mg/m3) Should be handled in the workplace as an extremely toxic substance.
NIOSH IDLH: N.D. See: IDLH INDEX


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
A harmful concentration of airborne particles can be reached quicklywhen dispersed.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the skin , the respiratory tract and severely to the eyes

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged inhalation exposure may cause asthma. See Notes.
PHYSICAL
PROPERTIES
Boiling point: 390C
Melting point: 161-163.5C
Solubility in water: reaction
Vapour pressure, kPa at 25C: negligible
Relative vapour density (air = 1): 6.6
Flash point:
227C o.c.
ENVIRONMENTAL
DATA

N O T E S
The symptoms of allergic reaction do not become manifest until 4 to 12 hours. The occupational exposure limit value should not be exceeded during any part of the working exposure.
ADDITIONAL INFORMATION


ICSC: 0345 TRIMELLITIC ANHYDRIDE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.