International Chemical Safety Cards

m-TOLUIDINE ICSC: 0342
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
3-Aminotoluene
m-Methylaniline
1-Amino-3-methylbenzene
C7H9N / C6H4CH3NH2
Molecular mass: 107.2
6 Poison placard ICSC #    0342
CAS #     108-44-1
RTECS # XU2800000
UN #        1708
EC #         612-024-00-4
November 27, 2009 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray, foam, powder, carbon dioxide
EXPLOSION Above 85C explosive vapour/air mixtures may be formed.
Above 85C use a closed system, ventilation.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
STRICT HYGIENE!
IN ALL CASES CONSULT A DOCTOR!
 •INHALATION Blue lips or finger nails. Blue skin. Confusion. Dizziness. Headache. Shortness of breath. Weakness. Convulsions. Nausea. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention.
 •SKIN Redness. (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
 •EYES Redness. Pain.
Safety goggles.
Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
 •INGESTION Blue lips or fingernails. Blue skin. Dizziness. Headache. Laboured breathing (Further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Refer immediately for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment.
Provision to contain effluent from fire extinguishing. Separated from strong oxidants, strong acids, food and feedstuffs . Well closed. Ventilation along the floor. Keep in the dark. Store in an area without drain or sewer access.
Do not transport with food and feedstuffs.
T symbol
N symbol
R: 23/24/25-33-50
S: 1/2-28-36/37-45-61
UN Hazard Class: 6.1
UN Packing Group: II
Signal: Warning
Excl mark-Health haz-Enviro
Combustible liquid
Harmful if swallowed
May be harmful in contact with skin
Causes eye irritation
May cause damage to blood
Very toxic to aquatic life
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0342 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

m-TOLUIDINE ICSC: 0342
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PHYSICAL STATE; APPEARANCE:
COLOURLESS TO YELLOW LIQUID TURNS DARK ON EXPOSURE TO AIR AND LIGHT.

PHYSICAL DANGERS:
As a result of flow, agitation, etc., electrostatic charges can be generated.

CHEMICAL DANGERS:
The substance decomposes on heating or on burning producing toxic fumes including nitrogen oxides . Reacts with strong oxidants and strong acids . Attacks some forms of plastic .

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 2 ppm as TWA (skin) A4 (not classifiable as a human carcinogen); BEI issued (ACGIH 2009).
MAK not established.
OSHA PEL: none
NIOSH REL: See Appendix D
NIOSH IDLH: N.D. See: IDLH INDEX


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes and is mildly irritating to the skin . The substance may cause effects on the blood , resulting in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
L for rats/oral/14 days is 30 mg/kg bw
PHYSICAL
PROPERTIES
Boiling point: 203C
Melting point: -30C
Relative density (water = 1): 0.99
Solubility in water, g/100 ml at 25C: 0.1
(poor)
Vapour pressure, Pa at 25C: 17
Relative vapour density (air = 1): 3.7
Relative density of the vapour/air-mixture at 20C (air = 1): 1.00
Flashpoint: 85C c.c.
Auto-ignition temperature: 480C
Explosive limits, vol% in air: 1.1-6.6
Octanol/water partition coefficient as log Pow: 1.40
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is very toxic to aquatic organisms. It is strongly advised that this substance does not enter the environment.
N O T E S
Depending on the degree of exposure, periodic medical examination is indicated. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. The odour warning when the exposure limit value is exceeded is insufficient. Do NOT take working clothes home. See also ICSC 0341 o-Toluidine and 0343 p-Toluidine.
ADDITIONAL INFORMATION


ICSC: 0342 m-TOLUIDINE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.