International Chemical Safety Cards

PYRIDINE ICSC: 0323
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
Azine
Azabenzene
C5H5N
Molecular mass: 79.1
3 Flammable Liquid placard ICSC #    0323
CAS #     110-86-1
RTECS # UR8400000
UN #        1282
EC #         613-002-00-7
December 04, 2000 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Powder, alcohol-resistant foam, water in large amounts, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE


 •INHALATION Cough. Dizziness. Headache. Nausea. Shortness of breath. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.
 •SKIN MAY BE ABSORBED! Redness. Burning sensation (further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
 •EYES Redness. Pain.
Safety spectacles. or face shield.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION Abdominal pain. Diarrhoea. Vomiting. Weakness (further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Personal protection: self-contained breathing apparatus. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer.
Fireproof. Separated from strong oxidants, strong acids. Cool. Dry. Well closed.

F symbol
Xn symbol
R: 11-20/21/22
S: 2-26-28
UN Hazard Class: 3
UN Packing Group: II
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0323 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

PYRIDINE ICSC: 0323
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PHYSICAL STATE; APPEARANCE:
 COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
 The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
 The substance decomposes on burning producing toxic fumes ( nitrogen oxides and hydrogen cyanide - see ICSC # 0492). The substance is a weak base. Reacts violently with strong oxidants and strong acids .

OCCUPATIONAL EXPOSURE LIMITS:
 TLV: 1 ppm
(as TWA)
A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2005).
MAK: skin absorption (H);
Carcinogen category: 3B
(DFG 2009).
OSHA PEL: TWA 5 ppm (15 mg/m3)
NIOSH REL: TWA 5 ppm (15 mg/m3)
NIOSH IDLH: 1000 ppm See: 110861


ROUTES OF EXPOSURE:
 The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
 A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
 The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the central nervous system and gastrointestinal tract. Exposure far above the OEL could cause lowering of consciousness.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
 The substance may have effects on the central nervous system , liver , kidneys .
PHYSICAL
PROPERTIES
Boiling point: 115°C
Melting point: -42°C
Relative density (water = 1): 0.98
Solubility in water:
miscible
Vapour pressure, kPa at 20°C: 2.0
Relative vapour density (air = 1): 2.73
 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.03
Flash point:
20°C c.c.
Auto-ignition temperature: 482°C
Explosive limits, vol% in air: 1.8-12.4
Octanol/water partition coefficient as log Pow: 0.65
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is harmful to aquatic organisms.
N O T E S
Pyridine can normally be detected by odour at levels well below the TLV. However, perception of the odour may decline quickly. Depending on the degree of exposure, periodic medical examination is indicated.
Transport Emergency Card: TEC (R)-98

NFPA Code: H 2; F 3; R 0;
Card has been partially updated in January 2008: see Ingestion First Aid.
Card has been partially updated in April 2010: see Occupational Exposure Limits, Spillage Disposal.
ADDITIONAL INFORMATION


ICSC: 0323 PYRIDINE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.