International Chemical Safety Cards

PROPYLENEIMINE ICSC: 0322
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
2-Methylaziridine
Methylethylenimine
C3H7N
Molecular mass: 57.1
6 Poison placard 3 Flammable Liquid placard ICSC #    0322
CAS #     75-55-8
RTECS # CM8050000
UN #        1921 (inhibited)
EC #         613-033-00-6
May 04, 2010 Validated
Fa, rack 2005: TLV, EU classification, TEC updated; EINECS, MAK added
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking. NO contact with acid(s).
Water spray. Alcohol-resistant foam. Dry powder. NO carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive. Risk of fire and explosion on contact with acid(s), oxidants.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools.
In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.
EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
 •INHALATION Cough. Sore throat. Burning sensation. Shortness of breath. Laboured breathing. Nausea. Vomiting. Dizziness. Headache. Symptoms may be delayed.
Closed system.
Fresh air, rest. Half-upright position. Refer immediately for medical attention.
 •SKIN MAY BE ABSORBED! Redness. (Further see Inhalation).
Protective gloves. Protective clothing.
First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention.
 •EYES Redness. Pain. Blurred vision. replaced by 19115000 in update May 2010; 19105000 added (low LD5O) cause not corrosive.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION Sore throat. (Further see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Remove all ignition sources. Ventilation. Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. 2010 no data for this chem.
Fireproof. Separated from acids, oxidants food and feedstuffs Cool. Ventilation along the floor. Store in original container. Store only if stabilized.
Airtight. Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.
Note: E
F symbol
T+ symbol
N symbol
R: 45-11-26/27/28-41-51/53
S: 53-45-61
UN Hazard Class: 3
UN Subsidiary Risks: 6.1
UN Packing Group: I
Signal: Danger
Flame-Skull-Health haz
Highly flammable liquid and vapour
Fatal if swallowed
Fatal if inhaled vapour
Fatal in contact with skin
Causes skin irritation
Causes serious eye irritation
May cause cancer
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0322 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

PROPYLENEIMINE ICSC: 0322
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PHYSICAL STATE; APPEARANCE:
COLOURLESS OILY FUMING LIQUID , WITH PUNGENT ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance may polymerize under the influence of acid(s) with fire or explosion hazard. The substance decomposes on heating producing toxic fumes including nitrogen oxides . Attacks some forms of plastic , coatings and rubber .

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.2 ppm as TWA; 0.4 ppm as STEL; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2010).
MAK: skin absorption (H);
Carcinogen category: 2; Germ cell mutagen group: 3B;
(DFG 2009).
OSHA PEL: TWA 2 ppm (5 mg/m3) skin
NIOSH REL: Ca TWA 2 ppm (5 mg/m3) skin See Appendix A
NIOSH IDLH: Ca 100 ppm See: 75558


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation , through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is severely irritating to the eyes, the skin and the respiratory tract. Inhalation may cause lung oedema (see Notes). Medical observation is indicated. Exposure far above the OEL may result in death. considering AEGL-3 value for 10 min exposure = 170 ppm.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
This substance is possibly carcinogenic to humans.
PHYSICAL
PROPERTIES
Boiling point: 67C
Melting point: -63C
Relative density (water = 1): 0.8
Solubility in water:
miscible
Vapour pressure, kPa at 20C: 14.9
Relative vapour density (air = 1): 2.0
Relative density of the vapour/air-mixture at 20C (air = 1): 1.21
Flashpoint: -18C c.c.
cision nov 2007) and replaced by 12702000 in update May 2010
Octanol/water partition coefficient as log Pow: 0.13
Viscosity, mm2/s at 25 C: 0.6
ENVIRONMENTAL
DATA

N O T E S
Explosive limits are unknown in literature, although the substance is combustible and has a flash point < 61C. Reacts violently with fire extinguishing agents such as carbon dioxide. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Data on similar substances suggest that there may be environmental effects of this substance. An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert. Do NOT take working clothes home.
update May 2010
ADDITIONAL INFORMATION


ICSC: 0322 PROPYLENEIMINE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.