International Chemical Safety Cards

ETHYL CARBAMATE

ICSC: 0314

Carbamic acid ethyl ester
Ethyl urethane
Urethane
C₃H₇NO₂ / NH₂COOC₂H₅
Molecular mass: 89.09
ICSC #    0314
CAS #     51-79-6
RTECS # FA8400000
EC #         607-149-00-6
May 07, 2010 Validated

TYPES OF HAZARD/ EXPOSURE	ACUTE HAZARDS/ SYMPTOMS	PREVENTION	FIRST AID/ FIRE FIGHTING
FIRE	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION

EXPOSURE		AVOID ALL CONTACT!
•INHALATION		Local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
•SKIN		Protective gloves.	Rinse skin with plenty of water or shower.
•EYES		Face shield or eye protection in combination with breathing protection if powder.	Rinse with plenty of water (remove contact lenses if easily possible).
•INGESTION		Do not eat, drink, or smoke during work.	Rinse mouth.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Personal protection: Chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place.

See Chemical Dangers. Well closed. tible materials (see Notes) - deselected 1997;

T symbol
R: 45
S: 53-45
Signal: Danger
Excl mark-Health haz
May be harmful if swallowed
May cause cancer
May cause harm to breast-fed children
May cause damage to the nervous system

SEE IMPORTANT INFORMATION ON BACK

ICSC: 0314

Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

ETHYL CARBAMATE

ICSC: 0314

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PHYSICAL STATE; APPEARANCE:
ODOURLESS, COLOURLESS CRYSTALS, PELLETS OR WHITE GRANULAR POWDER.

PHYSICAL DANGERS:

CHEMICAL DANGERS:
The substance decomposes on heating, producing toxic fumes , including nitrogen oxides . Reacts with strong oxidants , strong acids and strong bases . -2;

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: skin absorption (H);
Carcinogen category: 2; Germ cell mutagen group: 3A;
(DFG 2009).

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the nervous system. Exposure could cause lowering of consciousness. ence: The substance may cause effects on the central nervous system andliver. to select. No indications in literature of CNS-effects after normal routes of exposure. In rats, i.p. injections are use for inducing narcosis. A peculiar characteristic of urethane is represented by its ability to induce a surgical plane of anesthesia without affecting neurotransmission in various subcortical areas and the peripheral nervous system. This makes urethane a suitable general anesthetic nervous systems and accounts for the preservation of a number of reflex responses in urethane anesthetized animals.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
This substance is probably carcinogenic to humans. 35000

PHYSICAL
PROPERTIES

Boiling point: 185°C
Melting point: 49°C
Relative density (water = 1): 0.98
Solubility in water, g/100 ml: 200
Vapour pressure, Pa at 20°C: 5

Relative vapour density (air = 1): 3.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point:
92°C c.c.
Octanol/water partition coefficient as log Pow: -0.15

ENVIRONMENTAL
DATA

N O T E S

Do NOT take working clothes home. ay enhance absorption through skin.

ADDITIONAL INFORMATION

ICSC: 0314	ETHYL CARBAMATE
(C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE:

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.