International Chemical Safety Cards

ETHYL CARBAMATE ICSC: 0314
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
Carbamic acid ethyl ester
Ethyl urethane
Urethane
C3H7NO2 / NH2COOC2H5
Molecular mass: 89.09
ICSC #    0314
CAS #     51-79-6
RTECS # FA8400000
EC #         607-149-00-6
May 07, 2010 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION


EXPOSURE
AVOID ALL CONTACT!

 •INHALATION
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
 •SKIN
Protective gloves.
Rinse skin with plenty of water or shower.
 •EYES
Face shield or eye protection in combination with breathing protection if powder.
Rinse with plenty of water (remove contact lenses if easily possible).
 •INGESTION
Do not eat, drink, or smoke during work.
Rinse mouth.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Personal protection: Chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place.
See Chemical Dangers. Well closed. tible materials (see Notes) - deselected 1997;

T symbol
R: 45
S: 53-45
Signal: Danger
Excl mark-Health haz
May be harmful if swallowed
May cause cancer
May cause harm to breast-fed children
May cause damage to the nervous system
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0314 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

ETHYL CARBAMATE ICSC: 0314
I

M

P

O

R

T

A

N

T


D

A

T

A
PHYSICAL STATE; APPEARANCE:
ODOURLESS, COLOURLESS CRYSTALS, PELLETS OR WHITE GRANULAR POWDER.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on heating, producing toxic fumes , including nitrogen oxides . Reacts with strong oxidants , strong acids and strong bases . -2;

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: skin absorption (H);
Carcinogen category: 2; Germ cell mutagen group: 3A;
(DFG 2009).


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by ingestion.

INHALATION RISK:
Evaporation at 20C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the nervous system. Exposure could cause lowering of consciousness. ence: The substance may cause effects on the central nervous system andliver. to select. No indications in literature of CNS-effects after normal routes of exposure. In rats, i.p. injections are use for inducing narcosis. A peculiar characteristic of urethane is represented by its ability to induce a surgical plane of anesthesia without affecting neurotransmission in various subcortical areas and the peripheral nervous system. This makes urethane a suitable general anesthetic nervous systems and accounts for the preservation of a number of reflex responses in urethane anesthetized animals.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
This substance is probably carcinogenic to humans. 35000
PHYSICAL
PROPERTIES
Boiling point: 185C
Melting point: 49C
Relative density (water = 1): 0.98
Solubility in water, g/100 ml: 200
Vapour pressure, Pa at 20C: 5
Relative vapour density (air = 1): 3.1
Relative density of the vapour/air-mixture at 20C (air = 1): 1.00
Flash point:
92C c.c.
Octanol/water partition coefficient as log Pow: -0.15
ENVIRONMENTAL
DATA

N O T E S
Do NOT take working clothes home. ay enhance absorption through skin.
ADDITIONAL INFORMATION


ICSC: 0314 ETHYL CARBAMATE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.