International Chemical Safety Cards

HYDRAZINE ICSC: 0281
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
Diamide
Diamine
Nitrogen hydride
(anhydrous)
N2H4 / H2NNH2
Molecular mass: 32.1
6 Poison placard 3 Flammable Liquid placard 8 Corrosive placard ICSC #    0281
CAS #     302-01-2
RTECS # MU7175000
UN #        2029
EC #         007-008-00-3
November 25, 2009 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Flammable.
NO open flames, NO sparks, and NO smoking.
Alcohol-resistant foam, foam. water spray, dry powder, carbon dioxide.
EXPLOSION Above 40°C explosive vapour/air mixtures may be formed. Risk of fire and explosion on contact with many materials.
Above 40°C use a closed system, ventilation, and explosion-proof electrical equipment.
In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.
EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
 •INHALATION Cough. Burning sensation. Headache. Confusion. Drowsiness. Nausea. Shortness of breath. Convulsions. Unconsciousness.
Closed system and ventilation.
Fresh air, rest. Half-upright position. Refer immediately for medical attention.
 •SKIN MAY BE ABSORBED! Redness. Pain. Skin burns.
Protective gloves. Protective clothing.
First rinse with plenty of water, then remove contaminated clothes and rinse again. (See Notes) . Refer immediately for medical attention.
 •EYES Redness. Pain. Blurred vision. Severe burns.
Face shield and eye protection in combination with breathing protection.
Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
 •INGESTION Burns in mouth and throat. Abdominal pain. Diarrhoea. Vomiting. Shock or collapse. Further (see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Give nothing to drink. Do NOT induce vomiting. Refer immediately for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking liquid in sealable non-metallic containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT absorb in saw-dust or other combustible absorbents. Do NOT let this chemical enter the environment.
Fireproof. Separated from acids, metals , oxidants , food and feedstuffs . Keep under inert gas. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.
Special material. Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.
Note: E
T symbol
N symbol
R: 45-10-23/24/25-34-43-50/53
S: 53-45-60-61
UN Hazard Class: 8
UN Subsidiary Risks: 3 and 6.1
UN Packing Group: I
Signal: Danger
Flame-Corr-Skull-Health haz-Enviro
Flammable liquid and vapour
Fatal in contact with skin
Fatal if inhaled vapour
Toxic if swallowed
Causes severe skin burns and eye damage
May cause allergic skin reaction
Suspected of causing genetic defects
Suspected of causing cancer
Causes damage to liver and central nervous system
Causes damage to liver, lung, kidneys and central nervous system through prolonged or repeated exposure
Very toxic to aquatic life with long lasting effects
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0281 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

HYDRAZINE ICSC: 0281
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PHYSICAL STATE; APPEARANCE:
COLOURLESS , FUMING , OILY AND HYGROSCOPIC LIQUID , WITH PUNGENT ODOUR.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes producing ammonia, hydrogen and nitrogen oxides , causing fire and explosion hazard. The substance is a strong reducing agent and reacts violently with oxidants. The substance is a medium strong base. Reacts violently with acids, many metals, metal oxides and porous materials causing fire and explosion hazard. Air or oxygen is not required for decomposition.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.01 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2009).
MAK: skin absorption (H); sensitization of skin (Sh);
Carcinogen category: 2;
(DFG 2009).
OSHA PEL: TWA 1 ppm (1.3 mg/m3) skin
NIOSH REL: Ca C 0.03 ppm (0.04 mg/m3) 2-hour See Appendix A
NIOSH IDLH: Ca 50 ppm See: 302012


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Serious local effects by all routes of exposure.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is corrosive to the eyes, the skin and the respiratory tract. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. Corrosive on ingestion. The substance may cause effects on the liver and central nervous system . Exposure may result in death.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the liver , kidneys , and central nervous system . This substance is possibly carcinogenic to humans. 813020 yotoxic effects in animals studies at maternal toxic doses. Peer-review decision not to select
PHYSICAL
PROPERTIES
Boiling point: 114°C
Melting point: 2°C
Relative density (water = 1): 1.01
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 2.1
Relative vapour density (air = 1): 1.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 40°C c.c.
Auto-ignition temperature: 270°C
Explosive limits, vol% in air: 4.7-100
Octanol/water partition coefficient as log Pow: -2.1
Viscosity, mm²/s at 20°C: 0.0009
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is very toxic to aquatic organisms. It is strongly advised that this substance does not enter the environment.
N O T E S
Auto-ignition temperature varies from 24°C on a rusty iron surface to 270°C on glass surface. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. The odour warning when the exposure limit value is exceeded is insufficient. Rinse contaminated clothes with plenty of water because of fire hazard. Do NOT take working clothes home. Other UN numbers are: UN 2030 Hydrazine aqueous solution, with more than 37% hydrazine by mass, having a flash-point of not more than 60 °C: hazard class: 8, subsdiary risks: 3 and/or 6.1, packing group: I; Hydrazine aqueous solution, with more than 37% hydrazine by mass: hazard class: 8, subsdiary risk: 6.1, packing group: II-III. UN 3293 Hydrazine, aqueous solutions with not more than 37% of hydrazine, hazard class: 6.1, packing group: III. Other CAS-numbers are: 7803-57-8 for the 64% aqueous solution and 10217-52-4 for the 55% aqueous solution. nsit. ot to select, because after rinsing (24509000) this watersoluble substance should have been washed out and does not need storage in sealable container... can be given for GABA-neurotransmitter effects of hydrazine.
NFPA Code: H4; F4; R3
ADDITIONAL INFORMATION


ICSC: 0281 HYDRAZINE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.