International Chemical Safety Cards

BENZIDINE

ICSC: 0224

(1,1'-Biphenyl)-4,4'-diamine
4,4'-Diaminobiphenyl
p-Diaminodiphenyl
C₁₂H₁₂N₂ / NH₂C₆H₄C₆H₄NH₂
Molecular mass: 184.2

ICSC #    0224
CAS #     92-87-5
RTECS # DC9625000
UN #        1885
EC #         612-042-00-2
March 15, 1995 Validated

TYPES OF HAZARD/ EXPOSURE	ACUTE HAZARDS/ SYMPTOMS	PREVENTION	FIRST AID/ FIRE FIGHTING
FIRE	Combustible. See Notes. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, carbon dioxide.
EXPLOSION

EXPOSURE		AVOID ALL CONTACT!	IN ALL CASES CONSULT A DOCTOR!
•INHALATION		Closed system and ventilation.	Fresh air, rest. Refer for medical attention.
•SKIN	MAY BE ABSORBED!	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
•EYES		Face shield or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION		Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place.

Separated from strong oxidants, food and feedstuffs . Keep in the dark. Well closed.

Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.
Note: E
T symbol
N symbol
R: 45-22-50/53
S: 53-45-60-61
UN Hazard Class: 6.1
UN Packing Group: II

SEE IMPORTANT INFORMATION ON BACK

ICSC: 0224

Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

BENZIDINE

ICSC: 0224

I

M

P

O

R

T

A

N

T

D

A

T

A

PHYSICAL STATE; APPEARANCE:
WHITE OR REDDISH CRYSTALLINE POWDER, TURNS DARK ON EXPOSURE TO AIR AND LIGHT.

PHYSICAL DANGERS:

CHEMICAL DANGERS:
The substance decomposes on heating and on burning producing toxic fumes including nitrogen oxides . Reacts violently with strong oxidants, especially nitric acid.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: (skin) A1 (confirmed human carcinogen); (ACGIH 2004).
MAK: skin absorption (H);
Carcinogen category: 1;
(DFG 2004).
OSHA PEL: 1910.1010 See Appendix B See Appendix C
NIOSH REL: Ca See Appendix A See Appendix C
NIOSH IDLH: Ca N.D. See: IDLH INDEX

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
This substance is carcinogenic to humans.

PHYSICAL
PROPERTIES

Boiling point: 401°C
Melting point: (see Notes) 128°C
Relative density (water = 1): 1.25
Solubility in water:
none

Relative vapour density (air = 1): 6.36
Octanol/water partition coefficient as log Pow: 1.34

ENVIRONMENTAL
DATA

The substance is toxic to aquatic organisms.

N O T E S

Given melting point when anhydrous and rapidly heated, when slowly heated: 115-120°C. Addition of small amounts of a flammable substance or an increase in the oxygen content of the air strongly enhances combustibility. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.

Transport Emergency Card: TEC (R)-61GT2-II

ADDITIONAL INFORMATION

ICSC: 0224	BENZIDINE
(C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE:

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.