International Chemical Safety Cards ARSINE ICSC: 0222 Arsenic trihydride Hydrogen arsenide Arsenic hydride AsH3 Molecular mass: 77.9 (cylinder) ICSC #    0222 CAS #     7784-42-1 RTECS # CG6475000 UN #        2188 EC #         033-006-00-7 March 13, 2001 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Extremely flammable. Explosive. NO open flames, NO sparks, and NO smoking. Shut off supply; if not possible and no risk to surroundings, let the fire burn itself out; in other cases extinguish with powder, carbon dioxide. EXPLOSION Gas/air mixtures are explosive. Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding) if in liquid state. Do NOT expose to friction or shock. In case of fire: keep cylinder cool by spraying with water. Combat fire from a sheltered position. EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Abdominal pain. Confusion. Dizziness. Headache. Nausea. Shortness of breath. Vomiting. Weakness. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN ON CONTACT WITH LIQUID: FROSTBITE. Cold-insulating gloves. Protective clothing. ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention.  •EYES ON CONTACT WITH LIQUID: FROSTBITE. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Remove all ignition sources. Close cylinder or remove to open and safe place. If in liquid state: do NOT wash away into sewer. NEVER direct water jet on liquid. Do NOT let this chemical enter the environment. Gas-tight chemical protection suit including self-contained breathing apparatus. Fireproof if in building. Cool. Ventilation along the floor. F+ symbol T+ symbol N symbol R: 12-26-48/20-50/53 S: 1/2-9-16-28-33-36/37-45-60-61 UN Hazard Class: 2.3 UN Subsidiary Risks: 2.1 SEE IMPORTANT INFORMATION ON BACK ICSC: 0222 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards ARSINE ICSC: 0222 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS COMPRESSED LIQUEFIED GAS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: The gas is heavier than air and may travel along the ground; distant ignition possible. As a result of flow, agitation, etc., electrostatic charges can be generated. CHEMICAL DANGERS: The substance decomposes on heating and under the influence of light and moisture producing toxic arsenic fumes. Reacts with strong oxidants , causing explosion hazard. May explosively decompose on shock, friction, or concussion. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.05 ppm as TWA; Intended change ( TLV: 0.005 ppm (ACGIH 2005). MAK: IIb (not established but data is available) (DFG 2007). OSHA PEL: TWA 0.05 ppm (0.2 mg/m3) NIOSH REL: Ca C 0.002 mg/m3 15-minute See Appendix A NIOSH IDLH: Ca 3 ppm See: 7784421 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation. INHALATION RISK: A harmful concentration of this gas in the air will be reached very quickly on loss of containment. EFFECTS OF SHORT-TERM EXPOSURE: Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the blood , resulting in destruction of blood cells and kidney failure. The effects may be delayed. Exposure may result in death. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: This substance is carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: -62°C Melting point: -116°C Solubility in water, ml/100 ml at 20°C: 20 Vapour pressure, kPa at 20°C: 1043 Relative vapour density (air = 1): 2.7 Flash point: Flammable Gas Explosive limits, vol% in air: 4.5-78 ENVIRONMENTAL DATA It is strongly advised that this substance does not enter the environment. N O T E S The symptoms of poisoning do not become manifest until a few hours or even a few days have passed. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Turn leaking cylinder with the leak up to prevent escape of gas in liquid state. Also consult ICSC 0013 Arsenic. Card has been partly updated in October 2005. See sections Occupational Exposure Limits, Emergency Response. Transport Emergency Card: TEC (R)-20G2TF NFPA Code: H 4; F 4; R 2; ADDITIONAL INFORMATION ICSC: 0222 ARSINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.