International Chemical Safety Cards

DIAZINON ICSC: 0137
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
O,O-Diethyl-O-(2-isopropyl-6-methylpyrimidin-4-yl) phosphorothioate
Phosphorothioic acid O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) ester
C12H21N2O3PS / (CH3)2CHC4N2H(CH3)OPS(OC2H5)2
Molecular mass: 304.4
6 Harmful - Stow Away from Foodstuffs placard 6 Poison placard Marine Pollutant placard ICSC #    0137
CAS #     333-41-5
RTECS # TF3325000
UN #        3018
EC #         015-040-00-4
October 29, 2004 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, water spray, foam, carbon dioxide .
EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents.


EXPOSURE
AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!
IN ALL CASES CONSULT A DOCTOR!
 •INHALATION Pupillary constriction, muscle cramp, excessive salivation. Laboured breathing. Nausea. Vomiting. Dizziness. Convulsions. Unconsciousness.
Ventilation, local exhaust, or breathing protection. Avoid inhalation of mist .
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
 •SKIN MAY BE ABSORBED! Redness. Pain. (See Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
 •EYES Redness. Pain.
Face shield, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION Abdominal cramps. Diarrhoea. (Further see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Collect leaking liquid in sealable containers. Absorb remaining liquid in dry sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment.
Provision to contain effluent from fire extinguishing. Separated from strong oxidants, strong acids, bases , food and feedstuffs . Keep in a well-ventilated room.
Do not transport with food and feedstuffs.
Severe marine pollutant.
Xn symbol
N symbol
R: 22-50/53
S: 2-24/25-60-61
UN Hazard Class: 6.1
UN Packing Group: III
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0137 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

DIAZINON ICSC: 0137
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PHYSICAL STATE; APPEARANCE:
OILY COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. TECHNICAL PRODUCT: PALE YELLOW TO DARK BROWN.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on heating above 120C producing toxic fumes including nitrogen oxides , phosphorous oxides and sulfur oxides . Reacts with strong acids and alkalis with possible formation of highly toxic tetraethyl thiopyrophosphates. Reacts with strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: (Inhalable vapor and aerosol) 0.01 mg/m; (skin); A4; BEI issued; (ACGIH 2004).
MAK: (as inhalable fraction of the aerosol) 0.1 mg/m; Skin absorption;
Peak limitation category: II(2); Pregnancy risk group: C;
(DFG 2004).
OSHA PEL: none
NIOSH REL: TWA 0.1 mg/m3 skin
NIOSH IDLH: N.D. See: IDLH INDEX


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20C ; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is mildly irritating to the eyes and the skin . The substance may cause effects on the nervous system , resulting in convulsions and respiratory depression . Cholinesterase inhibitor. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Cholinesterase inhibitor; cumulative effect is possible: see Acute Hazards/Symptoms.
PHYSICAL
PROPERTIES
Decomposes below boiling point at 120C
Relative density (water = 1): 1.1
Solubility in water, g/100 ml at 20C: 0.006
Vapour pressure, Pa at 20C: negligible
Octanol/water partition coefficient as log Pow: 3.11
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is very toxic to aquatic organisms. This substance may be hazardous in the environment; special attention should be given to birds and honey bees. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal.
N O T E S
Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home.
Transport Emergency Card: TEC (R)-61GT6-III
ADDITIONAL INFORMATION


ICSC: 0137 DIAZINON
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.