International Chemical Safety Cards CHLOROTHALONIL ICSC: 0134 Tetrachloroisophthalonitrile 2,4,5,6-Tetrachloro-1,3-benzenedicarbonitrile 2,4,5,6-Tetrachloro-3-cyanobenzonitrile C8Cl4N2 Molecular mass: 265.9 ICSC #    0134 CAS #     1897-45-6 RTECS # NT2600000 UN #        2588 EC #         608-014-00-4 November 26, 2009 Validated Fi, review at IHE: 10/09/89 TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. Water spray, foam, powder, carbon dioxide. EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents. EXPOSURE AVOID ALL CONTACT!  •INHALATION Local exhaust or breathing protection. Fresh air, rest.  •SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Pain. Blurred vision. Safety spectacles or eye protection in combination with breathing protection if powder. Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.  •INGESTION Burning sensation in the throat and chest. Abdominal pain. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: Chemical protection suit,protective gloves. Do NOT let this chemical enter the environment. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs . Store in an area without drain or sewer access. Do not transport with food and feedstuffs. Marine pollutant. T+ symbol N symbol R: 26-37-40-41-43-50/53 S: 2-28-36/37/39-45-60-61 UN Hazard Class: 6.1 Signal: Danger Skull-Enviro Fatal if inhaled (dust) Causes mild skin irritation Causes serious eye irritation May cause allergic skin reaction May cause respiratory irritation Very toxic to aquatic life SEE IMPORTANT INFORMATION ON BACK ICSC: 0134 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards CHLOROTHALONIL ICSC: 0134 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: ODOURLESS COLOURLESS CRYSTALS. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing toxic and corrosive fumes including hydrogen chloride and nitrogen oxides. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK: sensitization of skin (Sh); Carcinogen category: 3B; (DFG 2009). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation. INHALATION RISK: A harmful concentration of airborne particles can be reached quickly when dispersed. EFFECTS OF SHORT-TERM EXPOSURE: The substance is severely irritating to the eyes and is mildly irritating to the skin. The substance irritates the respiratory tract. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. PHYSICAL PROPERTIES Boiling point: 350°C Melting point: 250-251°C Relative density (water = 1): 1.8 Solubility in water, g/100 ml at 25°C: (none) <0.01 Vapour pressure, Pa at 40°C: <1.3 negligible Octanol/water partition coefficient as log Pow: 3.05 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal. N O T E S Carrier solvents used in commercial formulations may change physical and toxicological properties. ADDITIONAL INFORMATION ICSC: 0134 CHLOROTHALONIL (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.