International Chemical Safety Cards BENZO(a)PYRENE ICSC: 0104 Benz(a)pyrene 3,4-Benzopyrene Benzo(d,e,f)chrysene C20H12 Molecular mass: 252.3 ICSC #    0104 CAS #     50-32-8 RTECS # DJ3675000 EC #         601-032-00-3 October 17, 2005 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. Water spray, foam, powder, carbon dioxide. EXPLOSION EXPOSURE See EFFECTS OF LONG-TERM OR REPEATED EXPOSURE. AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN!  •INHALATION Local exhaust or breathing protection. Fresh air, rest.  •SKIN MAY BE ABSORBED! Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Safety goggles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Separated from strong oxidants. T symbol N symbol R: 45-46-60-61-43-50/53 S: 53-45-60-61 SEE IMPORTANT INFORMATION ON BACK ICSC: 0104 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards BENZO(a)PYRENE ICSC: 0104 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: PALE-YELLOW CRYSTALS PHYSICAL DANGERS: CHEMICAL DANGERS: Reacts with strong oxidants causing fire and explosion hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV: Exposure by all routes should be carefully controlled to levels as low as possible A2 (suspected human carcinogen); (ACGIH 2005). MAK: Carcinogen category: 2; Germ cell mutagen group: 2; (DFG 2005). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. EFFECTS OF SHORT-TERM EXPOSURE: EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: This substance is carcinogenic to humans. May cause heritable genetic damage to human germ cells. Animal tests show that this substance possibly causes toxicity to human reproduction or development. PHYSICAL PROPERTIES Boiling point: 496°C Melting point: 178.1°C Density: 1.4 g/cm³ Solubility in water: none (<0.1 g/100 ml) Vapour pressure : negligible Octanol/water partition coefficient as log Pow: 6.04 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish, in plants and in molluscs. The substance may cause long-term effects in the aquatic environment. N O T E S Do NOT take working clothes home. Benzo(a)pyrene is present as a component of polycyclic aromatic hydrocarbons (PAHs) in the environment, usually resulting from the incomplete combustion or pyrolysis of organic matters, especially fossil fuels and tobacco. ADDITIONAL INFORMATION ICSC: 0104 BENZO(a)PYRENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.