International Chemical Safety Cards QUINOLINE ICSC: 0071 1-Benzazene Benzo(b)pyridine 1-Azanaphthalene Leucoline C9H7N Molecular mass: 129.2 ICSC #    0071 CAS #     91-22-5 RTECS # VA9275000 UN #        2656 November 14, 2008 Validated Pu, hed in Series 1. TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. water spray, foam, powder, carbon dioxide EXPLOSION Above 101°C explosive vapour/air mixtures may be formed. Above 101°C use a closed system, ventilation. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT!  •INHALATION Cough. Sore throat. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Safety spectacles . Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention.  •INGESTION Sore throat. Do not eat, drink, or smoke during work. Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Provision to contain effluent from fire extinguishing. Separated from strong oxidants, acids, anhydrides and food and feedstuffs . Dry. Keep in the dark. Well closed. Store in an area without drain or sewer access. Do not transport with food and feedstuffs. UN Hazard Class: 6.1 UN Packing Group: III Signal: Danger Skull-Health haz-Enviro Toxic if swallowed Harmful in contact with skin Causes mild skin irritation Causes eye irritation Suspected of causing cancer Suspected of causing genetic defects Very toxic to aquatic life SEE IMPORTANT INFORMATION ON BACK ICSC: 0071 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards QUINOLINE ICSC: 0071 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS HYGROSCOPIC LIQUID , WITH CHARACTERISTIC ODOUR. TURNS BROWN AFTER EXPOSURE TO LIGHT. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating and on burning producing toxic fumes including nitrogen oxides . Reacts with strong oxidants , acids and anhydrides . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes and the skin . EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver. This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: 238°C Melting point: -15°C Relative density (water = 1): 1.09 Solubility in water, g/100 ml at 20°C: 0.61 (very poor) Vapour pressure, Pa at 20°C: 8 Relative vapour density (air = 1): 4.5 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flashpoint: 101°C c.c. Auto-ignition temperature: 480°C Explosive limits, vol% in air: 1.2-7 Octanol/water partition coefficient as log Pow: 2.06 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. It is strongly advised that this substance does not enter the environment. N O T E S Health effects of exposure to the substance have not been investigated adequately. Depending on the degree of exposure, periodic medical examination is indicated. Transport Emergency Card: TEC (R)-61GT1-III NFPA Code: H3; F2; R0; ADDITIONAL INFORMATION ICSC: 0071 QUINOLINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.