International Chemical Safety Cards NITROBENZENE ICSC: 0065 C6H5NO2 Molecular mass: 123.1 ICSC #    0065 CAS #     98-95-3 RTECS # DA6475000 UN #        1662 EC #         609-003-00-7 April 06, 2006 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Water spray. Alcohol-resistant foam. Dry powder. Carbon dioxide. EXPLOSION Above 88°C explosive vapour/air mixtures may be formed. Risk of fire and explosion (see Chemical Dangers). Above 88°C use a closed system, ventilation. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Headache. Blue lips or finger nails. Blue skin. Dizziness. Nausea. Weakness. Confusion. Convulsions. Unconsciousness. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.  •SKIN MAY BE ABSORBED! (Further see Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION (see Inhalation). Do not eat, drink, or smoke during work. Rinse mouth. Give a slurry of activated charcoal in water to drink. Rest. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. Separated from combustible and reducing substances, strong oxidants, strong acids, food and feedstuffs . Store in an area without drain or sewer access. Do not transport with food and feedstuffs. T symbol N symbol R: 23/24/25-40-48/23/24-51/53-62 S: 1/2-28-36/37-45-61 UN Hazard Class: 6.1 UN Packing Group: II Signal: Danger Skull-Health haz Harmful if swallowed Toxic if inhaled vapour Toxic in contact with skin Suspected of causing cancer Suspected of damaging fertility or the unborn child May cause damage to blood cells Harmful to aquatic life with long lasting effects SEE IMPORTANT INFORMATION ON BACK ICSC: 0065 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards NITROBENZENE ICSC: 0065 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: PALE YELLOW OILY LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: On combustion, forms toxic and corrosive fumes including nitrogen oxides. Reacts violently with strong oxidants and reducing agents causing fire and explosion hazard. Reacts violently with strong acids and nitrogen oxides causing explosion hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV: 1 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2005). MAK: skin absorption (H); Carcinogen category: 3B; BAT issued; (DFG 2006). EU OEL: 1 mg/m³, 0.2 ppm as TWA (skin) (EU 2006). OSHA PEL: TWA 1 ppm (5 mg/m3) skin NIOSH REL: TWA 1 ppm (5 mg/m3) skin NIOSH IDLH: 200 ppm See: 98953 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation through the skin and by ingestion INHALATION RISK: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the blood , resulting in the formation of methaemoglobin. Exposure could cause lowering of consciousness. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the blood , spleen and liver . This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development. PHYSICAL PROPERTIES Boiling point: 211°C Melting point: 5°C Relative density (water = 1): 1.2 Solubility in water, g/100 ml: 0.2 Vapour pressure, Pa at 20°C: 20 Relative vapour density (air = 1): 4.2 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flash point: 88°C c.c. Auto-ignition temperature: 480°C Explosive limits, vol% in air: 1.8-40 Octanol/water partition coefficient as log Pow: 1.86 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. It is strongly advised that this substance does not enter the environment. N O T E S Use of alcoholic beverages enhances the harmful effect. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Do NOT take working clothes home. Card has been partly updated in October 2006: see sections Occupational Exposure Limits. Transport Emergency Card: TEC (R)-61S1662 or 61GT1-II NFPA Code: H 3; F 2; R 1; Card has been partially updated in January 2008: see GHS classification. ADDITIONAL INFORMATION ICSC: 0065 NITROBENZENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.