Sulfuryl fluoride

CAS number: 2699–79–8

NIOSH REL: 5 ppm (20 mg/m³) TWA, 10 ppm (40 mg/m³) STEL

Current OSHA PEL: 5 ppm (20 mg/m³) TWA

1989 OSHA PEL: 5 ppm (20 mg/m³) TWA, 10 ppm (40 mg/m³) STEL

1993-1994 ACGIH TLV: 5 ppm (21 mg/m³) TWA, 10 ppm (42 mg/m³) STEL

Description of substance: Colorless, odorless gas.

LEL: Nonflammable Gas

Original (SCP) IDLH: 1,000 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the report by Taxay [1966] that less than 5% mortality resulted from exposure of animals for 3 hours to 1,000 ppm.

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Lethal concentration data:

Species	Reference	LC50 (ppm)	LCLo (ppm)	Time	Adjusted 0.5-hr LC (CF)	Derived value
Rat	Nitschke et al. 1986	991	-----	4 hr	1,982 ppm (2.0)	198 ppm
Mouse	Truhaut et al. 1973	-----	1,200	1 hr	1,500 ppm (1.25)	150 ppm
Rabbit	Truhaut et al. 1973	-----	5,000	1 hr	6,250 ppm (1.25)	625 ppm

Other animal data: It has been reported that less than 5% mortality resulted from exposure for 3 hours to 1,000 ppm [Taxay 1966].

Human data: None relevant for use in determining the revised IDLH.

Revised IDLH: 200 ppm Basis for revised IDLH: The revised IDLH for sulfuryl fluoride is 200 ppm based on acute inhalation toxicity data in animals [Nitschke et al. 1986; Truhaut et al. 1973].

REFERENCES:

1. Nitschke KD, Albee RR, Mattsson JL, Miller RR [1986]. Incapacitation and treatment of rats exposed to a lethal dose of sulfuryl fluoride. Fundam Appl Toxicol 7:664-670.

2. Taxay EP [1966]. Vikane inhalation. J Occup Med 8:425-426.

3. Truhaut R, Boudene C, Cluet JL [1973]. Toxicite de quelques derives gazeux fluores et oxyfluores du soufre. Arch Mal Prof 34(10-11):581-591 (in French).