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May 1994
 

Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs)


Sulfuryl fluoride

CAS number: 2699–79–8

NIOSH REL: 5 ppm (20 mg/m3) TWA, 10 ppm (40 mg/m3) STEL

Current OSHA PEL: 5 ppm (20 mg/m3) TWA

1989 OSHA PEL: 5 ppm (20 mg/m3) TWA, 10 ppm (40 mg/m3) STEL

1993-1994 ACGIH TLV: 5 ppm (21 mg/m3) TWA, 10 ppm (42 mg/m3) STEL

Description of substance: Colorless, odorless gas.

LEL: Nonflammable Gas

Original (SCP) IDLH: 1,000 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the report by Taxay [1966] that less than 5% mortality resulted from exposure of animals for 3 hours to 1,000 ppm.

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Lethal concentration data:

 

SpeciesReferenceLC50

(ppm)

LCLo

(ppm)

TimeAdjusted 0.5-hr

LC (CF)

Derived value
RatNitschke et al. 1986 991-----4 hr1,982 ppm (2.0)198 ppm
MouseTruhaut et al. 1973 -----1,2001 hr1,500 ppm (1.25)150 ppm
RabbitTruhaut et al. 1973 -----5,0001 hr6,250 ppm (1.25) 625 ppm

Other animal data: It has been reported that less than 5% mortality resulted from exposure for 3 hours to 1,000 ppm [Taxay 1966].

Human data: None relevant for use in determining the revised IDLH.

 

Revised IDLH: 200 ppm

Basis for revised IDLH: The revised IDLH for sulfuryl fluoride is 200 ppm based on acute inhalation toxicity data in animals [Nitschke et al. 1986; Truhaut et al. 1973].

REFERENCES:

1. Nitschke KD, Albee RR, Mattsson JL, Miller RR [1986]. Incapacitation and treatment of rats exposed to a lethal dose of sulfuryl fluoride. Fundam Appl Toxicol 7:664-670.

2. Taxay EP [1966]. Vikane inhalation. J Occup Med 8:425-426.

3. Truhaut R, Boudene C, Cluet JL [1973]. Toxicite de quelques derives gazeux fluores et oxyfluores du soufre. Arch Mal Prof 34(10-11):581-591 (in French).

 
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