Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home
May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)

llyl glycidyl ether

CAS number: 106-92-3

NIOSH REL: 5 ppm (22 mg/m3) TWA, 10 ppm (44 mg/m3) STEL [skin]

Current OSHA PEL: 10 ppm (45 mg/m3) CEILING

1989 OSHA PEL: 5 ppm (22 mg/m3) TWA, 10 ppm (44 mg/m3) STEL

1993-1994 ACGIH TLV: 5 ppm (23 mg/m3) TWA, 10 ppm (47 mg/m3) STEL

Description of substance: Colorless liquid with a pleasant odor.

LEL: Unknown

Original (SCP) IDLH: 270 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the mouse 4-hour LC50 of 270 ppm [Hine et al. 1956] cited in ACGIH [1971], AIHA [1965], and Patty [1963].

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA

Lethal concentration data:
  Adjusted  
  LC50 LCLo   0.5-hr Derived
Species Reference (ppm) (ppm) Time LC (CF) Value
Mouse Hine et al. 1956 270 ----- 4 hr 540 ppm (2.0) 54 ppm
Rat Hine et al. 1956 670 ----- 8 hr 1,675 ppm (2.5) 168 ppm

Human data: None relevant for determining the revised IDLH.

Revised IDLH: 50 ppm

Basis for revised IDLH: The revised IDLH for allyl glycidyl ether is 50 ppm based on acute inhalation toxicity data in animals [Hine et al. 1956]. This may be a conservative value due to the lack of relevant acute toxicity data for workers.

References:

  1. ACGIH [1971]. Allyl glycidyl ether. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 9.
  2. AIHA [1965]. Allyl glycidyl ether. In: Hygienic guide series. Am Ind Hyg Assoc J 26:89-91.
  3. Hine CH, Kodama JK, Wellington JS, Dunlap MK, Anderson HH [1956]. The toxicology of glycidol and some glycidyl ethers. AMA Arch Ind Health 14:250-264.
  4. Patty FA, ed. [1963]. Industrial hygiene and toxicology. 2nd rev. ed. Vol. II. Toxicology. New York, NY: Interscience Publishers, Inc., p. 1599.
 
Contact Us:
USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Road Atlanta, GA 30329-4027, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO