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Registry of Toxic Effects of Chemical Substances (RTECS)

Valeric acid

RTECS #

YV6100000

CAS #

109-52-4

Updated

February 2006

Molecular Weight

102.15

Molecular Formula

C5H10O2

Synonyms

1-Butanecarboxylic acid
Butanecarboxylic acid
Kyselina valerova (Czech)
n-Pentanoic acid
n-Valeric acid
Pentanoic acid
Propylacetic acid
Valerianic acid

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 7500 mg/kg (6-15D pregnant)Reproductive: Other effects on female

Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
NTIS** OTS0571218

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lethal concentration (50 percent kill): 4100 mg/m3/2H85GMAT -,119,1982
intraperitoneal/mouse lethal dose (50 percent kill): 3590 mg/kgJPPMAB 21,85,1969
intravenous/mouse lethal dose (50 percent kill): 1290 mg/kgBehavioral: Altered sleep time (including change in righting reflex)

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Respiratory depression
APTOA6 18,141,1961
oral/mouse lethal dose (50 percent kill): 600 mg/kg85GMAT -,119,1982
subcutaneous/mouse lethal dose (50 percent kill): 3590 mg/kgJPPMAB 21,85,1969

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWAMIHAB 21,100,1960

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 5 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 84212; Number of Industries 2; Total Number of Facilities 79; Number of Occupations 8; Total Number of Employees Exposed 4510; Total Number of Female Employees Exposed 780
National Occupational Hazard Survey 1974Hazard Code 84212; Number of Industries 1; Total Number of Facilities 21; Number of Occupations 3; Total Number of Employees Exposed 497

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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