CDC logo, Safer Healthier People  CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us






Uranium (IV) oxide

RTECS #: YR4705000

CAS #: 1344-57-6


UPDATE: February 2009 MW: 270.03 MF: O2U


NOTE:

TABLE OF CONTENTS:
  1. ACUTE TOXICITY DATA:
  2. OTHER MULTIPLE DOSE DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. REFERENCES:

SYNONYMS:

N/R N/R


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 375 mg/m3/2 hour Behavioral: Food intake (animal)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
JTEHF8 69,1629,2006


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
dog
lowest published toxic concentration: 5.8 mg/m3/2 year- intermittent Lung, Thorax, or Respiration: Other changes VCVN1* -,281,1988
inhalation
monkey
lowest published toxic concentration: 5.8 mg/m3/2 year- intermittent Lung, Thorax, or Respiration: Fibrosis (interstitial) VCVN1* -,281,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.2 mg(U)/m3;short term exposure limit 0.6 mg(U)/m3 DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed human carcinogen DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
ENTOX* -,406,2005
TOXICOLOGY REVIEW
HBTME* ,881,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - BELGIUM time-weighted average 0.2 mg(U)/m3, short term exposure limit 0.6 mg(U)/m3, MAR2002
Occupational Exposure Limit - KOREA time-weighted average 0.2 mg(U)/m3, short term exposure limit 0.6 mg(U)/m3, 2006
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.2 mg(U)/m3, carcinogen, JAN2002
Occupational Exposure Limit - SWITZERLAND MAK- week 0.2 mg(U)/m3, DEC2006


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

N/R


REFERENCES:

CODEN
REFERENCE

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
HBTME*
JTEHF8 Journal of Toxicology and Environmental Health, Part A. (Taylor & Francis, 47 Runway Rd., Suite G, Levittown, PA 19057) V.53- 1998-
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  Contact Us