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Titanium chloride (TiCl4)

RTECS #: XR1925000

CAS #: 7550-45-0


UPDATE: February 2009 MW: 189.70 MF: Cl4Ti


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Tetrachlorure de titane (French)
  2. Titaantetrachloride (Dutch)
  3. Titane (tetrachlorure de) (French)
  1. Titanio (tetracloruro di) (Italian)
  2. Titanium tetrachloride
  3. Titantetrachlorid (German)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lethal concentration (50 percent kill): 100 mg/m3/2 hour N/R 85GMAT -,111,1982
inhalation
rat
lethal concentration (50 percent kill): 400 mg/m3 N/R 85GMAT -,111,1982
skin
rabbit
lethal dose (50 percent kill): 3,160 mg/kg N/R ENTOX* -,195,2005


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 10 mg/m3/6 hour/2 year- intermittent Lung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Changes in lung weight

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TXAPA9 83,30,1986


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
ENTOX* -,195,2005
TOXICOLOGY REVIEW
HBTME* ,861,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - RUSSIA short term exposure limit 1 mg/m3, Skin, JUN2003


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84219;
Number of Industries 3;
Total Number of Facilities 62;
Number of Occupations 9;
Total Number of Employees Exposed 1,337
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84219;
Number of Industries 3;
Total Number of Facilities 81;
Number of Occupations 5;
Total Number of Employees Exposed 2,107;
Total Number of Female Employees Exposed 131


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

ATSDR TOXICOLOGY PROFILE (NTIS** PB/98/101082/AS)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in manufacture of TITANIUM metal and TITANIUM DIOXIDE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
HBTME*
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

Used in manufacture of TITANIUM metal and TITANIUM DIOXIDE

NIOSH PROFILE (TITANIUM AND ITS COMPOUNDS), SRC, 4/78

RTECS Compound Description:
   Primary Irritant

Click Here for Additional Information about RTECS

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