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Registry of Toxic Effects of Chemical Substances (RTECS)

Tin fluoride

RTECS #

XQ3450000

CAS #

7783-47-3

Updated

September 201

Molecular Weight

156.69

Molecular Formula

F2Sn

Synonyms

Fluoristan
Stannous fluoride
Tin bifluoride
Tin difluoride

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium6 µmol/plate (-enzymatic activation step)MUREAV 90,91,1981
sex chromosome loss and nondisjunctionoral/Drosophila melanogaster15 pph/24HFLUOA4 6,113,1973

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 16150 µg/kgDZZEA7 34,484,1979
oral/mouse lethal dose (50 percent kill): 184 mg/kgOYYAA2 2,411,1968
oral/rat lethal dose (50 percent kill): 360 mg/kgBehavioral: Food intake (animal)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
NTIS** OTS0555162

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lowest published toxic dose: 392 mg/kg/10D- intermittentKidney, Ureter, and Bladder: Other changes in urine composition

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other transferases
TOLED5 7,463,1981

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 2 mg(Sn)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 2.5 mg(F)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 27,237,1982
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 27,237,1982
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMSUDL 7,208,1987
TOXICOLOGY REVIEWHBTME* ,839,2007

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 2 mg(Sn)/m3DTLVS* 3,257,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2 mg(Sn)/m3, JUL2008
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2.5 mg(F)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 2 mg(Sn)/m3, Skin, MAR2002
Occupational Exposure Limit-BELGIUMtime-weighted average 2.5 mg(F)/m3, MAR2002
Occupational Exposure Limit-ECtime-weighted average 2.5 mg(F)/m3, JUN2000
Occupational Exposure Limit-FINLANDtime-weighted average 2.5 mg(F)/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 2.5 mg(F)/m3, FEB2006
Occupational Exposure Limit-GERMANYMAK 1 mg(F)/m3, inhal, 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 2 mg(Sn)/m3, short term exposure limit 8 mg(Sn)/m3, Skin, SEP2000
Occupational Exposure Limit-HUNGARYtime-weighted average 2.5 mg(F)/m3, short term exposure limit 10 mg(F)/m3, Skin, SEP2000
Occupational Exposure Limit-KOREAtime-weighted average 2 mg(Sn)/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 2.5 mg(F)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2.5 mg(F)/m3, JAN2002
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2 mg(Sn)/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.6 mg(F)/m3, JAN1999
Occupational Exposure Limit-NORWAYtime-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) 1 mg(HF)/m3, MAC(short term exposure limit) 3 mg(HF)/m3, JAN1999
Occupational Exposure Limit-POLANDtime-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 0.2 mg/m3, short term exposure limit 1 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 2 mg(F)/m3, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 1 mg(F)/m3, KZG-week 4 mg(F)/m3, inhal, skin, JAN2011
Occupational Exposure Limit-SWITZERLANDMAK-week 2 mg(Sn)/m3, KZG-week 4 mg(Sn)/m3, inhal, JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 2 mg(Sn)/m3, JAN1993
Occupational Exposure Limit-THAILANDtime-weighted average 2.5 mg(F)/m3, JAN1993
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 2.5 mg(F)/m3, JAN1993
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 2 mg(Sn)/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 2.5 mg(F)/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 2.5 mg(F)/m3, OCT2007
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 2 mg(Sn)/m3;short term exposure limit 4 mg(Sn)/m3, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 2 mg(Sn)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 2.5 mg(F)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 2 mg(Sn)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 2.5 mg(F)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 2 mg(Sn)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 2.5 mg(F)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 2 mg(Sn)/m3CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 2.5 mg(F)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO FLUORIDES, INORGANIC-air10H time-weighted average 2.5 mg(F)/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 69735; Number of Industries 1; Total Number of Facilities 146; Number of Occupations 2; Total Number of Employees Exposed 340; Total Number of Female Employees Exposed 257
National Occupational Hazard Survey 1974Hazard Code 69735; Number of Industries 2; Total Number of Facilities 40; Number of Occupations 3; Total Number of Employees Exposed 79

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Negative: N crassa-aneuploidy
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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