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Tin (IV) chloride (1:4)

RTECS #: XP8750000

CAS #: 7646-78-8


UPDATE: May 2009 MW: 260.49 MF: Cl4Sn


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. TUMORIGENIC DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. Etain (tetrachlorure d') (French)
  2. Libavius fuming spirit
  3. Stagno (tetracloruro di) (Italian)
  4. Stannane, tetrachloro -
  5. Stannic chloride
  1. Tin chloride
  2. Tin perchloride
  3. Tin tetrachloride
  4. Tintetrachloride (Dutch)
  5. Zinntetrachlorid (German)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
skin
human
5%/48 hour CODEDG 29,110,1993


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis human leukocyte 4 mg/L CYTBAI 56,23,1988


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 365 gm/kg/1 year- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Reproductive: Tumorigenic effects: Uterine tumors

Tumorigenic: Increased incidence of tumors in susceptible strains
HBTME* -,839,2007


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lethal concentration (50 percent kill): 2,300 mg/m3/10 minute N/R TOXID9 1,77,1981
intraperitoneal
mouse
lethal dose (50 percent kill): 99 mg/kg N/R TXAPA9 63,461,1982


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 166 mg/kg/4 week- intermittent Autonomic Nervous System: Sympathomimetic PJPPAA 41,7,1989


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 2 mg(Sn)/m3 DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
HBTME* ,839,2007
TOXICOLOGY REVIEW
HUTOX* -,515,1996


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 2 mg(Sn)/m3 DTLVS* 3,257,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 2 mg(Sn)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 2 mg(Sn)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 2 mg(Sn)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 2 mg(Sn)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 2 mg(Sn)/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 2 mg(Sn)/m3, Skin, MAR2002
Occupational Exposure Limit - FINLAND time-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - HUNGARY time-weighted average 2 mg(Sn)/m3, short term exposure limit 8 mg(Sn)/m3, Skin, SEP2000
Occupational Exposure Limit - KOREA time-weighted average 2 mg(Sn)/m3, 2006
Occupational Exposure Limit - NEW ZEALAND time-weighted average 2 mg(Sn)/m3, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 2 mg(Sn)/m3, JAN1993
Occupational Exposure Limit - POLAND time-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 2 mg(Sn)/m3,KZG- week 4 mg(Sn)/m3, DEC2006
Occupational Exposure Limit - THAILAND time-weighted average 2 mg(Sn)/m3, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 2 mg(Sn)/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 2 mg(Sn)/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80077;
Number of Industries 11;
Total Number of Facilities 408;
Number of Occupations 18;
Total Number of Employees Exposed 2,399
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80077;
Number of Industries 5;
Total Number of Facilities 201;
Number of Occupations 16;
Total Number of Employees Exposed 7,310;
Total Number of Female Employees Exposed 4,836


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA GENETOX PROGRAM 1988, Negative: B subtilis rec assay
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CODEDG Contact Dermatitis. Environmental and Occupational Dermatitis. (Munksgaard International Pub., c/o Publications Expediting Inc., 200 Meacham Ave., Elmont, NY 11003) V.1- 1975-
CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
HBTME*
HUTOX*
PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25-44, 1973-92. For publisher information, see PJPAE3
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

RTECS Compound Description:
   Tumorigen
   Mutagen
   Human Data
   Hormone

Click Here for Additional Information about RTECS

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