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Thiophosphoryl chloride

RTECS #: XN2930000

CAS #: 3982-91-0


UPDATE: February 2006 MW: 169.38 MF: Cl3PS


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Fosforthiochlorid (Czech)
  2. Phosphorothioic trichloride
  3. Phosphorothionic trichloride
  4. Phosphorous sulfochloride
  5. Phosphorous thiochloride
  6. Phosphorous trichloride sulfide
  1. Sulfidotrichlorid fosforecny (Czech)
  2. TL 262
  3. Thiochlorid fosforecny (Czech)
  4. Thiophosphoric trichloride
  5. Thiophosphoryl trichloride
  6. Trichlorophosphine sulfide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
guinea pig
lethal concentration (50 percent kill): 400 mg/m3 Behavioral: Somnolence (general depressed activity)

Behavioral: Excitement
GTPZAB 31(12),53,1987
inhalation
mouse
lethal concentration (50 percent kill): 630 mg/m3 N/R GTPZAB 31(12),53,1987
inhalation
rat
lethal concentration (50 percent kill): 20 ppm/4 hour N/R 28ZPAK -,17,1972
oral
guinea pig
lethal dose (50 percent kill): 520 mg/kg N/R GTPZAB 31(12),53,1987
oral
mouse
lethal dose (50 percent kill): 700 mg/kg N/R GTPZAB 31(12),53,1987
oral
rat
lethal dose (50 percent kill): 660 mg/kg N/R GTPZAB 31(12),53,1987


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 2,925 mg/kg/90 day- intermittent Endocrine: Changes in adrenal weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases
JJATDK 4,230,1984


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
AQMOAC #73-19,1973


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - RUSSIA short term exposure limit 0.5 mg/m3, Skin, JUN2003


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84222;
Number of Industries 1;
Total Number of Facilities 21;
Number of Occupations 2;
Total Number of Employees Exposed 62
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84222;
Number of Industries 2;
Total Number of Facilities 21;
Number of Occupations 14;
Total Number of Employees Exposed 1,944;
Total Number of Female Employees Exposed 187


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as intermediate
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
AQMOAC Air Quality Monographs. (Washington, DC) No.69-1 - No.75-25, 1969-75(?). Discontinued.
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-

Used as intermediate

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