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Registry of Toxic Effects of Chemical Substances (RTECS)

2,2'-(2,5,8,11-Tetraoxa-1,12-dodecane diyl)bisoxirane

RTECS #

XF0700000

CAS #

1954-28-5

Updated

February 2005

Molecular Weight

262.34

Molecular Formula

C12H22O6

Synonyms

1,2:15,16-Diepoxy-4,7,10,13-tetraoxahexadecane
1,2-Bis(2-(2,3-epoxypropoxy)ethoxy)ethane
2,2'-(2,5,8,11-Tetraoxadodecane-1,12-diyl)bisoxirane
4,7,10,13-Tetraoxahexadecane, 1,2:15,16-diepoxy- (8CI)
Ayerst 62013
Epodyl
Ethoglucid
Ethoglucide
Etoglucid
Etoglucide
ICI-32865
Oxirane, 2,2'-(2,5,8,11-tetraoxadodecane-1,12-diyl)bis- (9CI)
Triethylene glycol diglycidyl ether

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /rabbit 10 mg/24H open irritation test mildAIHAAP 23,95,1962

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium300 µg/plate (+enzymatic activation step)MUREAV 111,99,1983

Tumorigenic Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lowest published toxic dose: 3800 mg/kg/4WTumorigenic: Neoplastic by RTECS criteria

Lung, Thorax, or Respiration: Tumors
JNCIAM 36,915,1966

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lowest published lethal dose: 700 mg/kgIMEMDT 11,209,1976

Reviews

OrganizationStandardReference
International Agency for Research on Cancer (IARC)Cancer Review:Animal Limited EvidenceIMEMDT 11,209,1976
International Agency for Research on Cancer (IARC)Cancer Review:Human No Adequate DataIMEMDT 11,209,1976
International Agency for Research on Cancer (IARC)Cancer Review:Human No Adequate DataIMEMDT 71,1539,1999
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 71,1539,1999
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMEMDT 71,1539,1999
TOXICOLOGY REVIEWCREOH* 47,109,2003
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