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Registry of Toxic Effects of Chemical Substances (RTECS)

Sulfone, p-chlorophenyl 2,4,5-trichlorophenyl

RTECS #

WR5850000

CAS #

116-29-0

Updated

May 2007

Molecular Weight

356.04

Molecular Formula

C12H6Cl4O2S

Synonyms

2,4,4',5-Tetrachloor-difenyl-sulfon (Dutch)
2,4,4',5-Tetrachlor-diphenyl-sulfon (German)
2,4,4',5-Tetrachlorodiphenyl sulfone
2,4,4',5-Tetracloro-difenil-solfone (Italian)
2,4,5,4'-Tetrachlorodiphenyl sulfone
2,4,5,4'-Tetrachlorodiphenylsulphone
3,4,6,4'-Tetrachlor-diphenylsulfon (German)
4-Chlorophenyl 2,4,5-trichlorophenyl sulfone
Akaritox
Aredion
Benzene, 1,2,4-trichloro-5-((4-chlorophenyl)sulfonyl)-
Duphar
ENT 23,737
FMC 5488
Mition
NIA 5488
p-Chlorophenyl 2,4,5-trichlorophenyl sulfone
p-Chlorophenyl 2,4,5-trichlorophenyl sulphone
Polacaritox
Roztozol
Sulfone, 2,4,4',5-tetrachlorodiphenyl
Tedion
Tedion V-18
Tetradichlone
Tetradifon
Tetradiphon
Tetrafidon
V-18

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
sister chromatid exchangelymphocyte/human100 µmol/LARTODN 52,221,1983

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
subcutaneous/mouse 1953 mg/kg (6-14D pregnant)Reproductive: Effects on embryo or fetus: Extra embryonic structures (e.g., placenta, umbilical cord)NTIS** PB223-160

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/Dog lethal dose (50 percent kill): 2 gm/kgSPEADM 78-1,55,1978
oral/rat lethal dose (50 percent kill): 566 mg/kgWRPCA2 9,119,1970
skin/rabbit lethal dose (50 percent kill): 10 gm/kg28ZEAL 5,220,1976
unreported route/rat lethal dose (50 percent kill): 5 gm/kgRREVAH 36,240,1971

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 5040 mg/kg/12W- continuousLiver: Other changes

Liver: Changes in liver weight

Endocrine: Changes in thyroid weight
TXCYAC 1,113,1973

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWMUREAV 562,77,2004
TOXICOLOGY REVIEWMUTAEX 21,93,2006

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESCancelledRBREV* -,212,1998
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