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Sulfide, bis (2 - chloroethyl)

RTECS #: WQ0900000

CAS #: 505-60-2


UPDATE: May 2009 MW: 159.08 MF: C4H8Cl2S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. TUMORIGENIC DATA:
  6. ACUTE TOXICITY DATA:
  7. OTHER MULTIPLE DOSE DATA:
  8. REVIEWS:
  9. STANDARDS AND REGULATIONS:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. 1,1' - Thiobis (2 - chloroethane)
  2. 1 - Chloro - 2 - (beta - chloroethylthio) ethane
  3. 2,2' - Dichloro diethyl sulphide
  4. 2,2' - Dichlorodiethyl sulfide
  5. 2,2' - Dichloroethyl sulphide
  6. Bis (2 - chloroethyl) sulfide
  7. Bis (2 - chloroethyl) sulphide
  8. Bis (beta - chloroethyl) sulfide
  9. Di - 2 - chloroethyl sulfide
  10. Distilled mustard
  11. Gelbkreuz (Czech)
  12. HD
  13. Kampstoff lost
  14. Mustard HD
  15. Mustard gas
  1. Mustard vapor
  2. Mustard, sulfur
  3. S mustard
  4. S - Lost
  5. Schwefel - lost
  6. Sulfur mustard
  7. Sulfur mustard gas
  8. Sulphur mustard
  9. Sulphur mustard gas
  10. Yellow cross liquid
  11. Yperite
  12. beta,beta' - Dichloroethyl sulfide
  13. beta,beta - Dichlor - ethyl - sulphide
  14. bis (2 - chloroethyl) sulfide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
man
0.1 ppm/6 hour moderate NTIS** AD-A011-260
eye
rabbit
0.2 ppm/30 minute mild NTIS** AD-A011-260
eye
rabbit
0.2 ppm/2 minute mild NTIS** AD-A011-260
eye
rabbit
0.4 L/24 hour severe JAPTO* 20,S173,2000
skin
human
65 g severe NTIS** PB158-508
skin
man
2 ppm/1 hour severe NTIS** AD-A011-260
skin
mouse
0.8 mg/7 day severe TOXID9 72,162,2003
skin
mouse
160 g/24 hour severe TOXID9 66,161,2002
skin
mouse
250 g/10 minute open irritation test severe JAPTO* 26,81,2006
skin
mouse
0.8 mg/72 hour open irritation test severe JAPTO* 26,239,2006
skin
pigeon
400 L/2 minute severe TOXID9 66,163,2002
skin
pig
400 L/8 minute open irritation test severe TOXID9 -,27,2008
skin
rabbit
1 L/24 hour severe TOXID9 72,164,2003


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis inhalation
Drosophila melanogaster
10 pph/15 minute- intermittent PREBA3 62,271,1946/1947
cytogenetic analysis human leukocyte 4 mg/L PJPPAA 39,405,1987
cytogenetic analysis mouse leukocyte 20 g/L MUREAV 21,6,1973
cytogenetic analysis rat lymphocyte 20 ng/L MUREAV 22,207,1974
dominant lethal test inhalation
Drosophila melanogaster
10 pph/15 minute- intermittent PREBA3 62,271,1946/1947
dominant lethal test inhalation
rat
100 g/m3/12 week- continuous MUREAV 21,13,1973
DNA adduct human other cell types 100 mol/L/5 minute CBINA8 138,231,2001
DNA adduct mouse Ascites tumor 2 mg/kg BIJOAK 80,496,1961
DNA damage chicken leukocyte 30 mmol/L TELEAY (29),2477,1975
DNA damage human other cell types 1 mol/L MUREAV 294,235,1993
DNA damage human HeLa cell 2 mg/L CBINA8 4,297,1971/1972
DNA damage mouse lymphocyte 1 mg/L BBACAQ 179,179,1969
DNA damage rat liver 80 mol/L/18 hour TXAPA9 176,24,2001
DNA damage Saccharomyes cerevisiae 500 mol/L CBINA8 44,27,1983
DNA inhibition human other cell types 500 nmol/L TIVIEQ 6,245,1992
DNA inhibition human HeLa cell 75 mg/L IUSMDJ 9,41,1979
DNA repair Escherichia coli 5 g/well MUREAV 46,53,1977
unscheduled DNA synthesis human HeLa cell 200 mg/L NATUAS 218,970,1968
unscheduled DNA synthesis mammal (species unspecified) lymphocyte 750 nmol/L CHRTBC 3,162,1972
host-mediated assay mouse
leukocyte
100 mg/kg MUREAV 21,6,1973
host-mediated assay mouse
Escherichia coli
8 mg/kg CNREA8 34,3073,1974
mutation in microorganisms Escherichia coli 8 mg/L (+enzymatic activation step) CNREA8 34,3073,1974
mutation in microorganisms Neurospora crassa 200 mol/L/30 minute (-enzymatic activation step) PNASA6 35,581,1949
mutation in microorganisms Salmonella typhimurium 10 g/plate (+enzymatic activation step) MUREAV 257,307,1991
micronucleus test intraperitoneal
mouse
8 mg/kg MUREAV 257,307,1991
micronucleus test oral
mouse
10 mg/kg MUREAV 257,307,1991
mutation in mammalian somatic cells mouse leukocyte 20 g/L MUREAV 21,6,1973
other mutation test systems human HeLa cell 75 mg/L IUSMDJ 9,41,1979
sister chromatid exchange human leukocyte 8 mg/L PJPPAA 39,405,1987
sex chromosome loss and nondisjunction inhalation
Drosophila melanogaster
10 pph/15 minute- intermittent PREBA3 62,271,1946/1947
specific locus test parenteral
Drosophila melanogaster
300 mol/L MUREAV 13,19,1971
heritable translocation test inhalation
Drosophila melanogaster
10 pph/15 minute- intermittent PREBA3 62,271,1946/1947


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 20 mg/kg (6-15 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
TJADAB 33,70C,1986
oral
rat
lowest published toxic dose: 25 mg/kg (10 week male) Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea)

Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)
NTIS** AD-A214-556
oral
rat
lowest published toxic dose: 68,800 g/kg (multigeneration) Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Delayed effects
REPTED 10,311,1996
oral
rabbit
lowest published toxic dose: 11,200 g/kg (6-18 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) TJADAB 33,70C,1986


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lowest published toxic concentration: 1,250 mg/m3/15 minute- continuous Tumorigenic: Neoplastic by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Blood: Leukemia
PSEBAA 82,457,1953
inhalation
rat
lowest published toxic concentration: 100 g/m3/1 year- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Skin and Appendages: Tumors
NTIS** AD-A011-260
inhalation
rat
lowest published toxic dose: 100 g/m3/6.5 hour/1 year- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Skin and Appendages: Tumors
JTEHF8 59,471,2000
intravenous
mouse
lowest published toxic dose: 600 mg/kg/6 day- intermittent Tumorigenic: Neoplastic by RTECS criteria

Lung, Thorax, or Respiration: Tumors
JNCIAM 11,415,1950
subcutaneous
mouse
lowest published toxic dose: 6 mg/kg/6 week- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application
JNCIAM 14,131,1953


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
cat
lethal concentration (50 percent kill): 70 mg/m3/10 minute N/R NTIS** PB158-508
inhalation
dog
lethal concentration (50 percent kill): 70 mg/m3/10 minute N/R NTIS** PB158-508
inhalation
domestic animal
lethal concentration (50 percent kill): 190 mg/m3/10 minute N/R NTIS** PB158-508
inhalation
guinea pig
lethal concentration (50 percent kill): 200 mg/m3/10 minute N/R NTIS** PB158-508
inhalation
human
lowest published lethal concentration: 23 ppm/10 minute N/R NTIS** PB214-270
inhalation
monkey
lethal concentration (50 percent kill): 80 mg/m3/10 minute N/R NTIS** PB158-508
inhalation
mouse
lethal concentration (50 percent kill): 120 mg/m3/10 minute N/R NTIS** PB158-508
inhalation
mouse
lowest published lethal concentration: 3.9 mg/m3/10 minute N/R TOXID9 72,160,2003
inhalation
mouse
lowest published lethal concentration: 2.7 mg/m3/30 minute N/R TOXID9 72,160,2003
inhalation
mouse
lowest published lethal concentration: 2.1 mg/m3/1 hour N/R TOXID9 72,160,2003
inhalation
mouse
lowest published lethal concentration: 530 g/m3/4 hour N/R TOXID9 72,160,2003
inhalation
mouse
lowest published lethal concentration: 270 g/m3/8 hour N/R TOXID9 72,160,2003
inhalation
rat
lethal concentration (50 percent kill): 100 mg/m3/10 minute N/R NTIS** PB158-508
inhalation
rat
lethal concentration (50 percent kill): 5.6 mg/m3/4 hour N/R TOVEFN (5),31,2002
inhalation
rat
lethal dose (50 percent kill): 0.56 mg/kg N/R TOVEFN (5),31,2002
inhalation
rat
lethal concentration (75 percent kill): 6.1 mg/m3/4 hour N/R TOVEFN (5),31,2002
inhalation
rat
lethal concentration (25 percent kill): 4.8 mg/m3/4 hour Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Respiratory obstruction
TOVEFN (5),31,2002
inhalation
rat
lethal concentration (25 percent kill): 4.8 mg/m3/4 hour Liver: Fatty liver degeneration

Liver: Other changes

Blood: Hemorrhage
TOVEFN (5),31,2002
inhalation
rat
lethal concentration (25 percent kill): 4.8 mg/m3/4 hour Nutritional and Gross Metabolic: Weight loss or decreased weight gain TOVEFN (5),31,2002
inhalation
rabbit
lethal concentration (50 percent kill): 280 mg/m3/10 minute N/R NTIS** PB158-508
intraperitoneal
rat
lowest published toxic dose: 5 mg/kg Nutritional and Gross Metabolic: Weight loss or decreased weight gain TXCYAC 231,30,2007
intraperitoneal
rat
lowest published lethal dose: 10 mg/kg Brain and Coverings: Other degenerative changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
TXCYAC 231,30,2007
intraperitoneal
rat
lowest published toxic dose: 2.5 mg/kg Liver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
TXCYAC 231,30,2007
intratracheal
guinea pig
lethal dose (50 percent kill): 0.73 mg/kg Lung, Thorax, or Respiration: Bronchiolar constriction, including asthma

Lung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Changes in lung weight
INHTE5 16,537,2004
intratracheal
rat
lethal dose (50 percent kill): 0.82 mg/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Respiratory obstruction
TOVEFN (5),31,2002
intratracheal
rat
lethal dose (50 percent kill): 0.82 mg/kg Liver: Fatty liver degeneration

Liver: Other changes

Blood: Hemorrhage
TOVEFN (5),31,2002
intratracheal
rat
lethal dose (50 percent kill): 0.82 mg/kg Nutritional and Gross Metabolic: Weight loss or decreased weight gain TOVEFN (5),31,2002
intravenous
dog
lethal dose (50 percent kill): 200 g/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Nausea or vomiting
NTIS** PB158-507
intravenous
mouse
lethal dose (50 percent kill): 3.3 mg/kg N/R ENTOX* ,706,2005
intravenous
rat
lethal dose (50 percent kill): 700 g/kg N/R JPETAB 93,1,1948
intravenous
rat
lowest published toxic dose: 1 mg/kg/3 minute Lung, Thorax, or Respiration: Other changes TOXID9 72,163,2003
intravenous
rat
lowest published toxic dose: 3 mg/kg Lung, Thorax, or Respiration: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Biochemical: Metabolism (intermediary): Other proteins
CRTOEC 18,28,2005
intravenous
rat
lowest published toxic dose: 4 mg/kg Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Other proteins
TOXID9 78,389,2004
intravenous
rabbit
lethal dose (50 percent kill): 1,100 g/kg N/R JPETAB 93,1,1948
ocular
rabbit
lowest published toxic dose: 0.31 mL/kg Eye: Corneal damage TOXID9 1,99,2001
oral
human
lethal dose (50 percent kill): 700 g/kg N/R JTEHF8 59,471,2000
oral
mouse
lowest published toxic dose: 4.83 mg/kg Liver: Other changes

Blood: Luekopenia
TXAPA9 202,180,2005
oral
mouse
lowest published lethal dose: 8.1 mg/kg Liver: Other changes

Blood: Luekopenia

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TXAPA9 202,180,2005
oral
rat
lethal dose (50 percent kill): 17 mg/kg N/R JTEHF8 59,471,2000
oral
rat
lowest published lethal dose: 2.4 mg/kg N/R TXAPA9 202,180,2005
subcutaneous
dog
lowest published lethal dose: 5 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Nausea or vomiting
NTIS** PB158-507
subcutaneous
domestic animal
lethal dose (50 percent kill): 40 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Nausea or vomiting
NTIS** PB158-507
subcutaneous
guinea pig
lethal dose (50 percent kill): 20 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Nausea or vomiting
NTIS** PB158-507
subcutaneous
mouse
lethal dose (50 percent kill): 20 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Nausea or vomiting
NTIS** PB158-507
subcutaneous
mouse
lowest published toxic dose: 4.83 mg/kg Blood: Luekopenia TXAPA9 202,180,2005
subcutaneous
mouse
lowest published toxic dose: 9.6 mg/kg Blood: Luekopenia

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TXAPA9 202,180,2005
subcutaneous
mouse
lowest published lethal dose: 13.7 mg/kg Blood: Luekopenia

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TXAPA9 202,180,2005
subcutaneous
rat
lethal dose (50 percent kill): 1,500 g/kg Behavioral: Food intake (animal)

Gastrointestinal: Hypermotility, diarrhea

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
CNRMAW 25,141,1947
subcutaneous
rat
lowest published lethal dose: 3.4 mg/kg N/R TXAPA9 202,180,2005
subcutaneous
rabbit
lethal dose (50 percent kill): 20 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Nausea or vomiting
NTIS** PB158-507
skin
dog
lethal dose (50 percent kill): 20 mg/kg N/R NTIS** PB158-507
skin
domestic animal
lethal dose (50 percent kill): 50 mg/kg N/R NTIS** PB158-507
skin
guinea pig
lethal dose (50 percent kill): 20 mg/kg N/R NTIS** PB158-507
skin
human
lethal dose (50 percent kill): 100 mg/kg N/R JTEHF8 59,471,2000
skin
human
lowest published lethal dose: 64 mg/kg Olfaction: Other olfaction effects

Eye: Conjunctiva irritation

Behavioral: Convulsions or effect on seizure threshold
WHOTAC -,24,1970
skin
mouse
lethal dose (50 percent kill): 92 mg/kg N/R JPETAB 93,1,1948
skin
mouse
lowest published toxic dose: 1,600 g/kg Skin: After systemic exposure: Dermatitis, other TOXID9 72,163,2003
skin
mouse
lowest published toxic dose: 3,200 g/kg Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation TOXID9 44,159,2005
skin
mouse
lowest published toxic dose: 12.7 mg/kg Skin: After systemic exposure: Dermatitis, irritative TXAPA9 200,40,2004
skin
mouse
lowest published lethal dose: 4.8 mg/kg Liver: Other changes

Blood: Luekopenia

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TXAPA9 202,180,2005
skin
mouse
lowest published toxic dose: 3.2 mg/kg Skin: After topical application: Cutaneous sensitization (experimental) TOXID9 44,451,2005
skin
mouse
lowest published toxic dose: 7,812.5 g/kg Skin: After topical application: Primary irritation

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
JAPTO* 24,107,2004
skin
mouse
lowest published toxic dose: 0.2 mg/kg Skin: After topical application: Corrosive

Biochemical: Metabolism (intermediary): Other proteins

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 78,356,2004
skin
mouse
lowest published toxic dose: 1.6 mg/kg Skin: After topical application: Primary irritation

Biochemical: Metabolism (intermediary): Other proteins

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 78,389,2004
skin
mouse
lowest published toxic dose: 2.67 mg/kg/6 hour Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other hydrolases

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
JAPTO* 26,239,2006
skin
mouse
lowest published toxic dose: 2.67 mg/kg/72 hour Skin: After topical application: Primary irritation

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other hydrolases
JAPTO* 26,239,2006
skin
rat
lethal dose (50 percent kill): 5 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Nausea or vomiting
NTIS** PB158-507
skin
rat
lowest published lethal dose: 2.4 mg/kg N/R TXAPA9 202,180,2005
skin
rat
lethal dose (50 percent kill): 18 mg/kg N/R ENTOX* -,174,2005
skin
rabbit
lethal dose (50 percent kill): 40 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Nausea or vomiting
NTIS** PB158-507
skin
rabbit
lethal dose (50 percent kill): 100 mg/kg N/R ENTOX* -,174,2005


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
dog
lowest published toxic concentration: 100 g/m3/6 hour/52 week- intermittent Eye: Corneal damage NTIS** AD-A011-260
oral
rat
lowest published toxic dose: 35 mg/kg/14 day- intermittent Cardiac: Other changes

Blood: Hemorrhage
JTEHF8 59,471,2000
oral
rat
lowest published toxic dose: 19,500 g/kg/13 week- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain JJATDK 16,5,1996


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

International Agency for Research on Cancer (IARC) Cancer Review Human Sufficient Evidence IMSUDL 7,259,1987
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMSUDL 7,259,1987
International Agency for Research on Cancer (IARC) Cancer Review Group 1 IMSUDL 7,259,1987
TOXICOLOGY REVIEW
TXAPA9 184,116,2002
TOXICOLOGY REVIEW
EMCPT* 2,151,2005
TOXICOLOGY REVIEW
EMCPT* 2,151,2005
TOXICOLOGY REVIEW
SUOPH* 41,461,1997
TOXICOLOGY REVIEW
TXCYAC 214,198,2005
TOXICOLOGY REVIEW
CPEMM* 3,239,2002
TOXICOLOGY REVIEW
CHHSA* 9,6,2002
TOXICOLOGY REVIEW
ENTOX* -,319,2005
TOXICOLOGY REVIEW
ENTOX* -,319,2005
TOXICOLOGY REVIEW
ENTOX* -,319,2005
TOXICOLOGY REVIEW
TXCYAC 214,221,2005
TOXICOLOGY REVIEW
FCTOD7 44,1699,2006
TOXICOLOGY REVIEW
ENTOX* -,174,2005
TOXICOLOGY REVIEW
FCLPH* 19,713,2005
TOXICOLOGY REVIEW
SIMEJ* 48,392,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - FINLAND Carcinogen, JAN1999
Occupational Exposure Limit - SWEDEN Group B Carcinogen, JUN2005


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

ATSDR TOXICOLOGY PROFILE (NTIS** PB2004/100006)
EPA GENETOX PROGRAM 1988, Positive: D melanogaster-whole sex chrom. loss
EPA GENETOX PROGRAM 1988, Positive: D melanogaster-reciprocal translocation
EPA GENETOX PROGRAM 1988, Positive: L5178Y cells in vitro-TK test; N crassa-reversion
EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal
EPA GENETOX PROGRAM 1988, Positive/dose response: TRP reversion
EPA GENETOX PROGRAM 1988, Positive/limited: Carcinogenicity-mouse/rat
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a vesicant in chemical warfare and as a model compound in biological studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen


REFERENCES:

CODEN
REFERENCE

BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947-
BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906-
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969-
CHHSA* Chemical Health & Safety (Orlando, FL : Published by Elsevier Inc. for the ACS Division of Chemical Health and Safety) V.1- 1994-
CHRTBC Chromosomes Today. (George Allen & Unwin Ltd., 40 Museum St., London WC1A 1LU, UK) V.1- 1966-
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941-
CNRMAW Canadian Journal of Research, Section E, Medical Sciences. (Ottawa, Ont., Canada) V.22-28, 1944-50. For publisher information, see CJBIAE.
CPEMM* Clinical Pediatric Emergency Medicine (Philadelphia, PA : W.B. Saunders Co.)
CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988-
EMCPT* EMC-Toxicologie Pathologie (Elsevier) V.1- 2004-
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
FCLPH* Fundamental & Clinical Pharmacology (Oxford : Blackwell Science) 2001-
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979-
INHTE5 Inhalation Toxicology. (Published by Taylor & Francis Health, 11 New Fetter Lane, London EC4P 4EE) V.1- 1989-
IUSMDJ ICN-UCLA Symposia on Molecular and Cellular Biology. (Menlo Park, CA) V.1-23, 1974-81.
JAPTO* Journal of Applied Toxicology (John Wiley & Sons, Ltd., Oldlands Way Bognor Regis West Sussex, PO22 9SA England) V.1- 1981-
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8.
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
JTEHF8 Journal of Toxicology and Environmental Health, Part A. (Taylor & Francis, 47 Runway Rd., Suite G, Levittown, PA 19057) V.53- 1998-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25-44, 1973-92. For publisher information, see PJPAE3
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915-
PREBA3 Proceedings of the Royal Society of Edinburgh, Section B. (Edinburgh, Scotland, UK) V.61-74, 1943-74.
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987-
SIMEJ*
SUOPH* Survey of Ophthalmology (Elsevier Inc.) V.20- 1975-
TELEAY Tetrahedron Letters. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) 1959-
TIVIEQ Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987-
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Used as a vesicant in chemical warfare and as a model compound in biological studies

RTECS Compound Description:
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data
   Primary Irritant

ALT CAS #: 69020-37-7
Click Here for Additional Information about RTECS

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