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Registry of Toxic Effects of Chemical Substances (RTECS)

2,2'-Stilbenedisulfonic acid, 4,4'-bis((4-anilino-6-morpholino-s-triazin-2-yl)amino)-,disodium salt

RTECS #

WJ6147000

CAS #

16090-02-1; 12646-20-7

Updated

April 2012

Molecular Weight

925.00

Molecular Formula

C40H38N12O8S2·2Na

Synonyms

4,4'-Bis((4-anilino-6-morpholino-1,3,5-triazine-2-yl)amino)stilbene 2,2-disulfonate 2Na
Belotex KD
Blankophor BBH
Blankophor MBBH
C.I. Fluorescent Brightener 244
C.I. Fluorescent Brightener 250
C.I. Fluorescent Brightener 260
C.I. Fluorescent Brightener 71
Calcofluor White RC
Disodium 4,4'-bis((4-anilino-6-morpholino-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulfonate
FBA-260
Heliofor 3BC
Heliofor BDC
Hiltamine Arctic White DML
Leukopur PAM
MBBH 766
Mikephor TB
Phorwite MBBH 766
Stralex MD
Tinopal AMS
Tinopal DMS-X
Tinopal EMS

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/2S rinse mildTXAPA9 27,494,1974
eye /rabbit 0.1 gm mildHPV385 -,-,2005
skin /rabbit 50% moderateHPV385 -,-,2005

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/cat Lethal dose: >500 mg/kgCCECAU 7,91,1977
oral/guinea pig Lethal dose: >1 gm/kgCCECAU 7,91,1977
oral/mouse lethal dose (50 percent kill): >20 gm/kgSRTCAC 36(1-4),10,1989
oral/rabbit Lethal dose: >1 gm/kgCCECAU 7,91,1977
oral/rat lethal dose (50 percent kill): 7000 mg/kgHPV385 -,-,2005
skin/rabbit Lethal dose: >10 gm/kgTXAPA9 27,494,1974
skin/rat lethal dose (50 percent kill): >2000 mg/kgHPV385 -,-,2005

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
skin/rat lowest published toxic dose: 21 gm/kg/21D- intermittentKidney, Ureter, and Bladder: Changes in kidney weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases
KHZDAN 29(2),24,1986

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code M4765; Number of Industries 1; Total Number of Facilities 25; Number of Occupations 1; Total Number of Employees Exposed 414; Total Number of Female Employees Exposed 279
National Occupational Hazard Survey 1974Hazard Code M4765; Number of Industries 2; Total Number of Facilities 38; Number of Occupations 3; Total Number of Employees Exposed 759

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Inconclusive: Histidine reversion-Ames test
EPA GENETOX PROGRAM 1988, Inconclusive: S cerevisiae gene conversion
EPA GENETOX PROGRAM 1988, Negative: Rodent dominant lethal; In vitro SCE-nonhuman
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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