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Registry of Toxic Effects of Chemical Substances (RTECS)

Stannane, dibutylbis(lauroyloxy)-

RTECS #

WH7000000

CAS #

77-58-7

Updated

September 201

Molecular Weight

631.65

Molecular Formula

C32H64O4Sn

Synonyms

Bis(lauroyloxy)di(n-butyl)stannane
Butynorate
Cata-Chek 820
Davainex
DBTL
Dibutylbis(laurato)tin
Dibutylbis(lauroyloxy)tin
Dibutylstannium dilaurate
Dibutyltin dilaurate
Dibutyltin laurate
Dibutyltin n-dodecanoate
Dibutyl-zinn-dilaurat (German)
DXR 81
Fomrez sul-4
Kosmos 19
KS 20
Lankromark LT 173
Laudran di-n-butylcinicity (Czech)
Lauric acid, dibutylstannylene salt
Lauric acid, dibutyltin deriv.
Laustan-B
Mark 1038
Mark BT 11
Mark BT 18
Neostann U 100
Ongrostab BLTM
SM 2014C
Stabilizer D-22
Stanclere DBTL
Stannane, bis(dodecanoyloxy) di-n-butyl-
Stannane, bis(lauroyloxy)dibutyl-
Stannane, dibutylbis((1-oxododecyl)oxy)-
Stavincor 1200 SN
Therm chek 820
Thermolite T 12
Tin dibutyl dilaurate
Tin, dibutylbis(lauroyloxy)-
Tin, di-n-butyl-, di(dodecanoate)
Tinostat
TN 12
TN 12 (catalyst)
TVS Tin Lau
TVS-TL 700

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/24H moderate28ZPAK -,230,1972
skin /rabbit 500 mg severeNTIS** OTS0555424

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 50532 µg/kg (8D pregnant)Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
TXCYAC 85,149,1993

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mammal (species unspecified) lethal concentration (50 percent kill): 2400 mg/m3MTPEEI (4),36,1995
inhalation/mouse lethal concentration (50 percent kill): 150 mg/m3/2HBehavioral: Somnolence (general depressed activity)

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Blood: Changes in bone marrow not included in above
STGNBT -,66,1999
intraperitoneal/mouse lethal dose (50 percent kill): 180 mg/kgBehavioral: Muscle weakness

Lung, Thorax, or Respiration: Respiratory depression

Gastrointestinal: Changes in structure or function of salivary glands
MTPEEI (4),36,1995
intraperitoneal/rat lowest published lethal dose: 85 mg/kgBJPCAL 10,16,1955
intravenous/rat lethal dose (50 percent kill): 33 mg/kgLiver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Blood: Changes in bone marrow not included in above
STGNBT -,66,1999
oral/mouse lethal dose (50 percent kill): 210 mg/kgBehavioral: Tremor

Lung, Thorax, or Respiration: Respiratory depression

Gastrointestinal: Changes in structure or function of salivary glands
MTPEEI (4),36,1995
oral/rabbit lethal dose (50 percent kill): 100 mg/kgBehavioral: Somnolence (general depressed activity)

Liver: Fatty liver degeneration

Blood: Pigmented or nucleated red blood cells
STGNBT -,66,1999
oral/rat lethal dose (50 percent kill): 175 mg/kgARZNAD 10,44,1960
skin/rabbit Lethal dose: >2 gm/kgGastrointestinal: Hypermotility, diarrhea

Skin: After systemic exposure: Dermatitis, other

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
NTIS** OTS0555424

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 120 mg/kg/3D- intermittentBrain and Coverings: Other degenerative changes

Behavioral: Somnolence (general depressed activity)

Biochemical: Metabolism (intermediary): Lipids including transport
TOLED5 57,245,1991
oral/rat lowest published toxic dose: 262 mg/kg/15D- intermittentNutritional and Gross Metabolic: Weight loss or decreased weight gain

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
DCTODJ 4,75,1981
oral/rat lowest published toxic dose: 20 mg/kg/2W- intermittentEndocrine: Changes in thymus weightIITOEF 16,645,1994

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.1 mg(Sn)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-short term exposure limit 0.2 mg(Sn)/m3 (skin)DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWEVHPAZ 4,61,1973
TOXICOLOGY REVIEWEQSFAP 4,80,1975

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.1 mg(Sn)/m3DTLVS* 3,258,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.1 mg(Sn)/m3, short term exposure limit 0.2 mg(Sn)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.1 mg(Sn)/m3, short term exposure limit 0.2 mg(Sn)/m3, Skin, MAR2002
Occupational Exposure Limit-FRANCEVME 0.1 mg(Sn)/m3, VLE 0.2 mg(Sn)/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 0.1 mg(Sn)/m3, short term exposure limit 0.4 mg(Sn)/m3, Skin, SEP2000
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.1 mg(Sn)/m3, short term exposure limit 0.2 mg(Sn)/m3, skin, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.1 mg(Sn)/m3, JAN1999
Occupational Exposure Limit-SWITZERLANDceiling concentration 0.004 ppm (0.02 mg(Sn)/m3), skin, JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 0.1 mg(Sn)/m3, JAN1993
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.1 mg(Sn)/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.1 mg(Sn)/m3;short term exposure limit 0.2 mg(Sn)/m3, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.1 mg(Sn)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.1 mg(Sn)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.1 mg(Sn)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.1 mg(Sn)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ORGANOTIN COMPOUND-air10H time-weighted average 0.1 mg(Sn)/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 83554; Number of Industries 93; Total Number of Facilities 8868; Number of Occupations 64; Total Number of Employees Exposed 118739; Total Number of Female Employees Exposed 24525
National Occupational Hazard Survey 1974Hazard Code 83554; Number of Industries 19; Total Number of Facilities 413; Number of Occupations 30; Total Number of Employees Exposed 7628

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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