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Registry of Toxic Effects of Chemical Substances (RTECS)

Sorbic acid

RTECS #

WG2100000

CAS #

110-44-1; 91751-55-2

Updated

August 2009

Molecular Weight

112.14

Molecular Formula

C6H8O2

Synonyms

(E,E)-2,4-Hexadienoic acid
1,3-Pentadiene-1-carboxylic acid
2,4-Hexadienoic acid, (E,E)- (9CI)
2E,4E-Hexadienoic acid
2-Propenylacrylic acid
Acetic acid, (2-butenylidene)-
Acetic acid, crotylidene-
Hexadienic acid
Hexadienoic acid
Kyselina 1,3-pentadien-1-karboxylova (Czech)
Kyselina sorbova (Czech)
Panosorb
Sorbistat
trans,trans-Sorbic acid
trans-trans-2,4-Hexadienoic acid

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /man 150 mg/1H severeJPPMAB 10,719,1958
skin /rabbit 1 mg severeUCDS** 7/14/1965

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysislung/hamster1050 mg/LFCTOD7 22,501,1984
sister chromatid exchangelung/hamster1050 mg/LFCTOD7 22,501,1984

Tumorigenic Data and References

Route/OrganismDoseEffectReference
subcutaneous/rat lowest published toxic dose: 1040 mg/kg/65W- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application
BJCAAI 20,134,1966

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 2820 mg/kgJPPMAB 21,85,1969
intraperitoneal/rat lethal dose (50 percent kill): 800 mg/kg38MKAJ 2C,4953,1982
oral/mouse lethal dose (50 percent kill): 3200 mg/kg38MKAJ 2C,4953,1982
oral/rat lethal dose (50 percent kill): 7360 mg/kgJIHTAB 30,63,1948
skin/rabbit Lethal dose: >1 gm/kgUCDS** 7/14/1965
subcutaneous/mouse lethal dose (50 percent kill): 2820 mg/kgJPPMAB 21,85,1969

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWFCTOD7 46,2935,2008

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 81510; Number of Industries 45; Total Number of Facilities 4412; Number of Occupations 59; Total Number of Employees Exposed 69243; Total Number of Female Employees Exposed 21637
National Occupational Hazard Survey 1974Hazard Code 81510; Number of Industries 6; Total Number of Facilities 583; Number of Occupations 11; Total Number of Employees Exposed 4662

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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