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Sodium sulfide

RTECS #: WE1900000

CAS #: 16721-80-5


UPDATE: May 2008 MW: 56.06 MF: HNaS


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Sodium bisulfide
  2. Sodium hydrogen sulfide
  3. Sodium hydrosulfide
  1. Sodium mercaptan
  2. Sodium sulfhydrate
  3. Sodium mercaptide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
mutation in microorganisms Salmonella typhimurium 2 mol/plate (+enzymatic activation step) MUREAV 90,91,1981
sex chromosome loss and nondisjunction oral
Drosophila melanogaster
50 mmol/L MUREAV 90,91,1981
sex chromosome loss and nondisjunction multiple
Drosophila melanogaster
2,000 ppm ACBIEF 14(52),48,1985


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lethal dose (50 percent kill): 18 mg/kg Behavioral: Coma DCTODJ 1,327,1978
intraperitoneal
rat
lethal dose (50 percent kill): 14,600 g/kg N/R BCPCA6 38,973,1989
oral
rat
lowest published toxic dose: 1.85 g/kg Gastrointestinal: Other changes TXCYAC 241,11,2007
subcutaneous
mouse
lethal dose (50 percent kill): 200 mg/kg Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Lung, Thorax, or Respiration: Respiratory stimulation

Lung, Thorax, or Respiration: Other changes
JJPAAZ 3,99,1954


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lowest published toxic dose: 35 mg/kg/5 day- intermittent Brain and Coverings: Other degenerative changes

Biochemical: Metabolism (intermediary): Amino acids (including renal excretion)
NRTXDN 11,93,1990
intraperitoneal
rat
lowest published toxic dose: 67,500 g/kg/3 day- intermittent Brain and Coverings: Other degenerative changes

Biochemical: Metabolism (intermediary): Amino acids (including renal excretion)
NRTXDN 11,93,1990


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83515;
Number of Industries 5;
Total Number of Facilities 94;
Number of Occupations 10;
Total Number of Employees Exposed 359
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83515;
Number of Industries 18;
Total Number of Facilities 577;
Number of Occupations 34;
Total Number of Employees Exposed 12,517;
Total Number of Female Employees Exposed 4,278


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as depilatory
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

ACBIEF Actualidades Biologicas (Medellin, Colombia). (Universidad de Antioquia, Departamento de Biologia, Apartado Aereo 1226, Medellin, Colombia) V.1- 1972-
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958-
DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78-
JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NRTXDN Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-

Used as depilatory

NIOSH PROFILE (PHOTOGRAPHIC PROCESSING), FIRL, 4/78

NIOSH PROFILE (PULP AND PAPER MILLS), SRI, 2/77

RTECS Compound Description:
   Mutagen

ALT CAS #: 1310-76-5
Click Here for Additional Information about RTECS

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