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Sodium monohydrogen phosphate (2:1:1)

RTECS #: WC4500000

CAS #: 7558-79-4


UPDATE: May 2008 MW: 141.96 MF: HO4P2Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Dibasic sodium phosphate
  2. Disodium hydrogen phosphate
  3. Disodium monohydrogen phosphate
  4. Disodium orthophosphate
  5. Disodium phosphate
  6. Disodium phosphoric acid
  7. Exsiccated sodium phosphate
  1. Natriumphosphat (German)
  2. Phosphoric acid, disodium salt
  3. Soda phosphate
  4. Sodium hydrogen phosphate
  5. Sodium phosphate
  6. Sodium phosphate, dibasic


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
500 mg/24 hour mild 28ZPAK -,16,1972
skin
rabbit
500 mg/24 hour mild 28ZPAK -,16,1972


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intramuscular
rat
lowest published lethal dose: 1 gm/kg N/R BIZEA2 163,226,1925
intraperitoneal
rat
lowest published lethal dose: 1 gm/kg N/R BIZEA2 163,226,1925
intravenous
rabbit
lowest published lethal dose: 1,075 mg/kg Behavioral: Tetany HXPHAU 10,361,1950
oral
rat
lethal dose (50 percent kill): 17,000 mg/kg N/R USXXAM #6365129
subcutaneous
rat
lowest published lethal dose: 1 gm/kg N/R BIZEA2 163,226,1925


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intravenous
rat
lowest published toxic dose: 3,976 mg/kg/14 day- intermittent Kidney, Ureter, and Bladder: Changes primarily in glomeruli

Kidney, Ureter, and Bladder: Proteinuria
TOPADD 32,408,2004
intravenous
rat
lowest published toxic dose: 1,988 mg/kg/7 day- intermittent Kidney, Ureter, and Bladder: Proteinuria TOPADD 32,408,2004


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,318,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83514;
Number of Industries 85;
Total Number of Facilities 6,564;
Number of Occupations 60;
Total Number of Employees Exposed 57,176
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83514;
Number of Industries 166;
Total Number of Facilities 21,015;
Number of Occupations 135;
Total Number of Employees Exposed 1,230,592;
Total Number of Female Employees Exposed 912,048


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE

28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
BIZEA2 Biochemische Zeitschrift. (Berlin, Ger.) V.1-346, 1906-67. For publisher information, see EJBCAI.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
HXPHAU Handbuch der Experimentellen Pharmakologie. (Berlin, Ger.) New series: V.1-49, 1935-78. For publisher information, see HEPHD2.
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978-
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231)

Used in boiler compounds, cattle feed supplements, water treatment, buffer, leather tanning

RTECS Compound Description:
   Primary Irritant

Click Here for Additional Information about RTECS

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