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Registry of Toxic Effects of Chemical Substances (RTECS)

Sodium iodide

RTECS #

WB6475000

CAS #

7681-82-5

Updated

September 201

Molecular Weight

149.89

Molecular Formula

INa

Synonyms

Ioduril
Jodid sodny (Czech)
Natriumjodid (German)
Sodium iodine
Sodium monoiodide

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/24H moderate28ZPAK -,21,1972
skin /rabbit 500 mg/24H moderate28ZPAK -,21,1972

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/woman 9240 mg/kg (1-43W pregnant)Reproductive: Specific developmental abnormalities: Endocrine system

Reproductive: Effects on newborn: Other postnatal measures or effects
ADCHAK 38,526,1963

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse Lowest published lethal concentration: 50000 mg/m3/2HVCVN5* -,404,1989
intraperitoneal/mouse lethal dose (50 percent kill): 430 mg/kgPSEBAA 115,551,1964
intraperitoneal/rat lowest published toxic dose: 600 µg( intermittent)/kgEndocrine: Evidence of thyroid hypofunctionFATOAO 45,96,1982
intravenous/Dog lowest published lethal dose: 760 mg/kgHBAMAK 4,1289,1935
intravenous/rat lethal dose (50 percent kill): 1060 mg/kgAEPPAE 222,584,1954
oral/man lowest published toxic dose: 100 µL/kg/14D- intermittentEndocrine: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)
CLECAP 28,283,1988
oral/mouse lethal dose (50 percent kill): 1000 mg/kgVCVN5* -,404,1989
oral/rabbit lowest published lethal dose: 2362 mg/kgJPETAB 30,407,1927
oral/rat lethal dose (50 percent kill): 4340 mg/kg28ZPAK -,21,1972
oral/rat lowest published lethal dose: 1600 mg/kgVCVN5* -,404,1989

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 64267 µg/kg/14W- continuousEndocrine: Changes in thyroid weight

Blood: Other changes
JTEHD6 32,89,1991
oral/rat lowest published toxic dose: 84 gm/kg/28D- continuousSkin and Appendages: Other glands

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
PSEBAA 114,341,1963
oral/rat lowest published toxic dose: 7497 mg/kg/90D- continuousEndocrine: Changes in thyroid weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
ACEDAB 69,321,1972
oral/rat lowest published toxic dose: 6715.5 mg/kg/121D- continuousEndocrine: Changes in thyroid weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
ACEDAB 69,321,1972
oral/rat lowest published toxic dose: 840 mg/kg/12W- continuousEndocrine: Other changesEJEND* 137,89,1997
oral/rat lowest published toxic dose: 140 mg/kg/2W- intermittentLiver: Changes in liver weightTOXID9 72,284,2003

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.01 ppm (inhal, vapor)DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 1 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 69120; Number of Industries 14; Total Number of Facilities 1773; Number of Occupations 27; Total Number of Employees Exposed 63333; Total Number of Female Employees Exposed 49362
National Occupational Hazard Survey 1974Hazard Code 69120; Number of Industries 7; Total Number of Facilities 529; Number of Occupations 9; Total Number of Employees Exposed 6918

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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