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| UPDATE: May 2009 | MW: 22.99 | MF: Na |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intraperitoneal | mouse
lethal dose (50 percent kill): 4 gm/kg
|
N/R
|
85IXA4 -,704,1948
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | rat
lowest published toxic dose: 1,687.5 mg/kg/180 day- continuous
|
Cardiac: Changes in heart weight | Gastrointestinal: Other changes Blood: Changes in cell count (unspecified)
VCVN1* -,36,1988
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oral | rat
lowest published toxic dose: 1,575 mg/kg/12 week- continuous
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Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases | Biochemical: Metabolism (intermediary): Effect on mitochondrial function Biochemical: Neurotransmitters or modulators (putative): Catecholamine levels in CNS
VCVN1* -,36,1988
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REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
TOXICOLOGY REVIEW
|
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ENTOX* -,60,2005
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TOXICOLOGY REVIEW
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HTOPA* 1,595,2002
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STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
National Occupational Hazard Survey 1974
|
National Occupational Hazard Survey 1974: Hazard Code: 68765; | Number of Industries 7; Total Number of Facilities 381; Number of Occupations 9; Total Number of Employees Exposed 3,325
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 68765 |
 ;Number of Industries 179; Total Number of Facilities 23,017; Number of Occupations 79; Total Number of Employees Exposed 262,032; Total Number of Female Employees Exposed 34,622 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
|
Used as chemical intermediate and heat-transfer medium
|
EPA TSCA Section 8(d) unpublished health/safety studies
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
|
OSHA ANALYTICAL METHOD #ID122
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REFERENCES:
CODEN
|
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REFERENCE
85IXA4
|
"Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet,
D., and F. Bovet-Nitti, New York, S. Karger, 1948
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ENTOX*
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Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
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HTOPA*
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VCVN1*
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"Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous
substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.
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