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Sodium

RTECS #: VY0686000

CAS #: 7440-23-5


UPDATE: May 2009 MW: 22.99 MF: Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Natrium


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lethal dose (50 percent kill): 4 gm/kg N/R 85IXA4 -,704,1948


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 1,687.5 mg/kg/180 day- continuous Cardiac: Changes in heart weight

Gastrointestinal: Other changes

Blood: Changes in cell count (unspecified)
VCVN1* -,36,1988
oral
rat
lowest published toxic dose: 1,575 mg/kg/12 week- continuous Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases

Biochemical: Metabolism (intermediary): Effect on mitochondrial function

Biochemical: Neurotransmitters or modulators (putative): Catecholamine levels in CNS
VCVN1* -,36,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
ENTOX* -,60,2005
TOXICOLOGY REVIEW
HTOPA* 1,595,2002


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 68765;
Number of Industries 7;
Total Number of Facilities 381;
Number of Occupations 9;
Total Number of Employees Exposed 3,325
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 68765;
Number of Industries 179;
Total Number of Facilities 23,017;
Number of Occupations 79;
Total Number of Employees Exposed 262,032;
Total Number of Female Employees Exposed 34,622


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as chemical intermediate and heat-transfer medium
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
OSHA ANALYTICAL METHOD #ID122


REFERENCES:

CODEN
REFERENCE

85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
HTOPA*
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

Used as chemical intermediate and heat-transfer medium

NIOSH PROFILE (HEAVY METAL GREASES AND SOAPS), SRI, 2/77

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