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Registry of Toxic Effects of Chemical Substances (RTECS)

Silicate(2-), hexafluoro-, disodium

RTECS #

VV8410000

CAS #

16893-85-9; 1310-02-7; 39413-34-8

Updated

April 2013

Molecular Weight

188.07

Molecular Formula

F6Si·2Na

Synonyms

Destruxol applex
Disodium hexafluorosilicate (2-)
Disodium silicofluoride
Ens-zem weevil bait
ENT 1,501
Fluosilicate de sodium
Natriumsilicofluorid (German)
Ortho earwig bait
Ortho weevil bait
Prodan
PSC Co-Op weevil bait
Safsan
Salufer
Silicon sodium fluoride
Sodium fluosilicate
Sodium hexafluorosilicate
Sodium hexafluosilicate
Sodium silicofluoride
Sodium silicon fluoride
Super prodan

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg severeFCTOD7 20,573,1982
eye /rabbit 100 mg/4S rinse severeFCTOD7 20,573,1982
skin /rabbit 500 mg mildFCTOD7 20,563,1982

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/mouse lethal dose (50 percent kill): 70 mg/kgPeripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Ataxia

Behavioral: Muscle contraction or spasticity
GISAAA 53(11),80,1988
oral/rabbit lethal dose (50 percent kill): 125 mg/kgFMCHA2 -,C268,1991
oral/rat lethal dose (50 percent kill): 125 mg/kgARSIM* 20,21,1966
subcutaneous/frog lowest published lethal dose: 448 mg/kgCRSBAW 124,133,1937
subcutaneous/rat lowest published lethal dose: 70 mg/kgLiver: Fatty liver degeneration

Liver: Other changes

Kidney, Ureter, and Bladder: Changes primarily in glomeruli
JPETAB 39,246,1930
unreported route/human lowest published lethal dose: 5.7 mg/kgVCVN5* -,359,1989

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 248 mg/kg/30D- intermittentKidney, Ureter, and Bladder: Other changes in urine composition

Musculoskeletal: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases
GISAAA 53(11),80,1988

Reviews

OrganizationStandardReference
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 27,237,1982
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 27,237,1982
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMSUDL 7,208,1987
TOXICOLOGY REVIEWAMSSAQ 400,5,1963

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESCancelledRBREV* -,317,1998
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2.5 mg(F)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 2.5 mg(F)/m3, MAR2002
Occupational Exposure Limit-FINLANDtime-weighted average 2.5 mg(F)/m3, NOV2011
Occupational Exposure Limit-GERMANYMAK 1 mg(F)/m3, inhal, 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 2.5 mg(F)/m3, short term exposure limit 10 mg(F)/m3, Skin, SEP2000
Occupational Exposure Limit-MEXICOtime-weighted average 2.5 mg(F)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2.5 mg(F)/m3, JAN2002
Occupational Exposure Limit-RUSSIAshort term exposure limit 0.2 mg/m3, JUN2003
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 2.5 mg(F)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 2.5 mg(F)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 2.5 mg(F)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 2.5 mg(F)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO FLUORIDES, INORGANIC-air10H time-weighted average 2.5 mg(F)/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 84233; Number of Industries 74; Total Number of Facilities 8057; Number of Occupations 60; Total Number of Employees Exposed 79556; Total Number of Female Employees Exposed 22185
National Occupational Hazard Survey 1974Hazard Code 84233; Number of Industries 43; Total Number of Facilities 3995; Number of Occupations 50; Total Number of Employees Exposed 20064

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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