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Silane, triethoxy -

RTECS #: VV6682000

CAS #: 998-30-1


UPDATE: February 2008 MW: 164.31 MF: C6H16O3Si


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Triethoxysilane


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lethal concentration (50 percent kill): 500 mg/m3/2 hour Behavioral: Ataxia

Lung, Thorax, or Respiration: Acute pulmonary edema

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
TPKVAL 5,192,1963
inhalation
rat
lethal concentration (50 percent kill): 500 mg/m3/2 hour Behavioral: Ataxia

Lung, Thorax, or Respiration: Acute pulmonary edema

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
TPKVAL 5,192,1963
inhalation
rat
lethal concentration : 0.9 gm/m3 N/R TPKVAL 5,192,1963
inhalation
rat
lowest published lethal concentration: 0.2 gm/m3 N/R TPKVAL 5,192,1963
intravenous
mouse
lethal dose (50 percent kill): 180 mg/kg N/R CSLNX* NX#00018
skin
mouse
lowest published toxic dose: 100 pph Skin: After topical application: Primary irritation TPKVAL 5,192,1963
skin
rabbit
lowest published toxic dose: 100 pph Skin: After topical application: Primary irritation TPKVAL 5,192,1963


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 20 mg/m3/3 hour/22 week- intermittent Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Liver: Liver function tests impaired

Blood: Changes in leukocyte (WBC) count
TPKVAL 5,192,1963
inhalation
rat
lowest published toxic concentration: 0.2 gm/m3/45 day- intermittent Brain and Coverings: Changes in circulation

Blood: Hemorrhage

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TPKVAL 5,192,1963
inhalation
rat
lowest published toxic concentration: 0.2 gm/m3/30 day- intermittent Peripheral Nerve and Sensation: Recording from peripheral motor nerve TPKVAL 5,192,1963
inhalation
rat
lowest published toxic concentration: 0.7 gm/m3/61 day- intermittent Peripheral Nerve and Sensation: Recording from peripheral motor nerve TPKVAL 5,192,1963
inhalation
rat
lowest published toxic concentration: 0.7 gm/m3/153 day- intermittent Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Liver: Other changes

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
TPKVAL 5,192,1963


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - RUSSIA short term exposure limit 1 mg/m3, JUN2003


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961-

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