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Registry of Toxic Effects of Chemical Substances (RTECS)

Silane, triethoxy-

RTECS #

VV6682000

CAS #

998-30-1

Updated

February 2008

Molecular Weight

164.31

Molecular Formula

C6H16O3Si

Synonyms

Triethoxysilane

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lethal concentration (50 percent kill): 500 mg/m3/2HBehavioral: Ataxia

Lung, Thorax, or Respiration: Acute pulmonary edema

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
TPKVAL 5,192,1963
inhalation/rat Lowest published lethal concentration: 0.2 gm/m3TPKVAL 5,192,1963
inhalation/rat lethal concentration (50 percent kill): 500 mg/m3/2HBehavioral: Ataxia

Lung, Thorax, or Respiration: Acute pulmonary edema

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
TPKVAL 5,192,1963
intravenous/mouse lethal dose (50 percent kill): 180 mg/kgCSLNX* NX#00018

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 20 mg/m3/3H/22W- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Liver: Liver function tests impaired

Blood: Changes in leukocyte (WBC) count
TPKVAL 5,192,1963
inhalation/rat lowest published toxic concentration: 0.02 gm/m3/45D- intermittentBrain and Coverings: Changes in circulation

Blood: Hemorrhage

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TPKVAL 5,192,1963
inhalation/rat lowest published toxic concentration: 0.02 gm/m3/30D- intermittentPeripheral Nerve and Sensation: Recording from peripheral motor nerveTPKVAL 5,192,1963
inhalation/rat lowest published toxic concentration: 0.007 gm/m3/61D- intermittentPeripheral Nerve and Sensation: Recording from peripheral motor nerveTPKVAL 5,192,1963
inhalation/rat lowest published toxic concentration: 0.007 gm/m3/153D- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Liver: Other changes

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
TPKVAL 5,192,1963

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 1 mg/m3, JUN2003

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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