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Registry of Toxic Effects of Chemical Substances (RTECS)

Pyrrolidine

RTECS #

UX9650000

CAS #

123-75-1

Updated

February 2008

Molecular Weight

71.14

Molecular Formula

C4H9N

Synonyms

Azacyclopentane
Azolidine
Prolamine
Pyrrole, tetrahydro-
Tetrahydropyrrole
Tetramethylenimine

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lethal concentration (50 percent kill): 1300 mg/m3/2HBehavioral: Convulsions or effect on seizure threshold

Behavioral: Excitement

Vascular: Other changes
GTPZAB 18(2),29,1974
inhalation/mouse lethal concentration (50 percent kill): 1000 mg/m3TPKVAL 14,95,1975
intraperitoneal/mouse lethal dose (50 percent kill): 420 mg/kgJPETAB 88,82,1946
intravenous/mouse lethal dose (50 percent kill): 56 mg/kgCSLNX* NX#06769
oral/guinea pig lowest published lethal dose: 250 mg/kg85GMAT -,104,1982
oral/mammal (species unspecified) lethal dose (50 percent kill): 250 mg/kgGISAAA 39(4),86,1974
oral/mouse lethal dose (50 percent kill): 450 mg/kgBCFAAI 103,414,1964
oral/rabbit lowest published lethal dose: 250 mg/kg85GMAT -,104,1982
oral/rat lethal dose (50 percent kill): 300 mg/kgBehavioral: Convulsions or effect on seizure threshold

Behavioral: Excitement

Vascular: Other changes
GTPZAB 18(2),29,1974

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 2.6 mg/m3/182D- intermittentLiver: Other changes

Kidney, Ureter, and Bladder: Other changes

Reproductive: Paternal effects: Testes, epididymis, sperm duct
TPKVAL 14,95,1975

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 0.1 mg/m3, Skin, JUN2003

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Negative: Host-mediated assay
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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