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Registry of Toxic Effects of Chemical Substances (RTECS)

2-Propen-1-amine, N-2-propenyl-

RTECS #

UC6650000

CAS #

124-02-7

Updated

February 2008

Molecular Weight

97.18

Molecular Formula

C6H11N

Synonyms

Di-2-propenylamine

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 50 mg/20S rinse severeAEHLAU 1,343,1960
skin /rabbit 100 µg/24H open irritation testAIHAAP 23,95,1962

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mammal (species unspecified) lethal concentration (50 percent kill): 2100 mg/m3TPKVAL 14,80,1975
inhalation/man lowest published toxic concentration: 5 ppm/5MEye: Lacrimation

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
AEHLAU 1,343,1960
inhalation/rat lethal concentration (50 percent kill): 795 ppm/8HOlfaction: Other olfaction effects

Eye: Lacrimation

Lung, Thorax, or Respiration: Dyspnea
AEHLAU 1,343,1960
intraperitoneal/mouse lethal dose (50 percent kill): 187 mg/kgBehavioral: Tremor

Lung, Thorax, or Respiration: Respiratory depression

Gastrointestinal: Other changes
AEHLAU 1,343,1960
oral/mouse lethal dose (50 percent kill): 355 mg/kg85GMAT -,43,1982
oral/rat lethal dose (50 percent kill): 578 mg/kgBehavioral: Tremor

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Other changes
AEHLAU 1,343,1960
skin/rabbit lethal dose (50 percent kill): 280 µL/kgAIHAAP 23,95,1962
unreported route/mammal (species unspecified) lethal dose (50 percent kill): 350 mg/kgTPKVAL 14,80,1975

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 200 ppm/7H/50D- intermittentCardiac: Changes in heart weight

Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight
AEHLAU 1,343,1960

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWTXCYAC 44,129,1987

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 1 mg/m3, Skin, JUN2003

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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