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2 - Propanol, 1 - ethoxy -

RTECS #: UB5250000

CAS #: 1569-02-4


UPDATE: February 2008 MW: 104.17 MF: C5H12O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 1 - Ethoxy - 2 - propanol
  1. Propylene glycol ethyl ether


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
100 mg/24 hour moderate 85JCAE -,627,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
guinea pig
lowest published toxic concentration: 2,500 mg/m3 Eye: Conjunctiva irritation

Behavioral: General anesthetic
VCVGK* -,171,1984
inhalation
mouse
lowest published toxic concentration: 2,500 mg/m3 Eye: Conjunctiva irritation

Behavioral: General anesthetic
VCVGK* -,171,1984
inhalation
rat
lethal concentration (50 percent kill): >10,000 ppm/4 hour N/R NPIRI* 1,104,1974
inhalation
rabbit
lowest published toxic concentration: 2,500 mg/m3 Eye: Conjunctiva irritation

Behavioral: General anesthetic
VCVGK* -,171,1984
oral
rat
lethal dose (50 percent kill): 4,400 mg/kg N/R NPIRI* 1,104,1974
oral
rat
lethal dose (50 percent kill): 7,000 mg/kg Behavioral: General anesthetic VCVGK* -,171,1984
skin
rabbit
lethal dose (50 percent kill): 8,100 mg/kg N/R NPIRI* 1,104,1974


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
cat
lowest published toxic concentration: 5,100 mg/m3/8 hour/12 day- intermittent Lung, Thorax, or Respiration: Other changes

Kidney, Ureter, and Bladder: Other changes

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
VCVGK* -,171,1994
inhalation
guinea pig
lowest published toxic concentration: 5,100 mg/m3/8 hour/12 day- intermittent Lung, Thorax, or Respiration: Other changes

Kidney, Ureter, and Bladder: Other changes

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
VCVGK* -,171,1994


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - DENMARK time-weighted average 100 ppm (tentative), OCT 2002
Occupational Exposure Limit - SWITZERLAND MAK- week 50 ppm (220 mg/m3),KZG- week 100 ppm (440 mg/m3), Skin, DEC2006


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

RTECS Compound Description:
   Primary Irritant

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