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1,3 - Propanediol, 2 - ethyl - 2 - (hydroxymethyl) -

RTECS #: TY6470000

CAS #: 77-99-6


UPDATE: May 2008 MW: 134.20 MF: C6H14O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 1,1,1 - Tri (hydroxymethyl) propane
  2. 1,1,1 - Trimethylolpropane
  3. 1,1,1 - Tris (hydroxymethyl) propane
  4. 2 - Ethyl - 2 - (hydroxymethyl) - 1,3 - propanediol
  5. Ethriol
  6. Ethyltrimethylolmethane
  1. Ettriol
  2. Hexaglycerine
  3. TMP (alcohol)
  4. Trimethylolpropane
  5. Tris (hydroxymethyl) propane


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
mouse
lethal dose (50 percent kill): 13,700 mg/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea

Lung, Thorax, or Respiration: Respiratory depression
HYSAAV 32(5),288,1967
oral
mouse
lethal dose (50 percent kill): 14,000 mg/kg N/R VCVGK* -,158,1984
oral
rat
lethal dose (50 percent kill): 14,100 mg/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea

Lung, Thorax, or Respiration: Respiratory depression
HYSAAV 32(5),288,1967
oral
rat
lethal dose (50 percent kill): 14,000 mg/kg N/R VCVGK* -,158,1984


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 1,100 mg/m3/4 hour/106 day- intermittent Behavioral: Irritability

Blood: Other changes

Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth)
VCVGK* -,158,1994


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 5 mg/m3, 2003
Occupational Exposure Limit - RUSSIA short term exposure limit 50 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 5 mg/m3, JUN2005


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83589;
Number of Industries 28;
Total Number of Facilities 2,495;
Number of Occupations 54;
Total Number of Employees Exposed 33,290
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83589;
Number of Industries 48;
Total Number of Facilities 5,573;
Number of Occupations 43;
Total Number of Employees Exposed 74,356;
Total Number of Female Employees Exposed 12,646


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued.
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

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