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Registry of Toxic Effects of Chemical Substances (RTECS)

1,3-Propanediamine, N,N-dimethyl-

RTECS #

TX7525000

CAS #

109-55-7

Updated

August 2007

Molecular Weight

102.21

Molecular Formula

C5H14N2

Synonyms

1-Amino-3-dimethylaminopropane
3-(Dimethylamino)propylamine
N,N-Dimethyl-1,3-diaminopropane
N,N-Dimethyl-1,3-propanediamine
N,N-Dimethyl-1,3-propylenediamine
N,N-Dimethyl-N-(3-aminopropyl)amine
Propylamine, 3-(N,N-dimethylamino)-

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 5 mg moderateUCDS** 12/15/1971
skin /rabbit 100 µg/24H open irritation testAIHAAP 23,95,1962

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lethal dose (50 percent kill): 1870 mg/kgAIHAAP 23,95,1962
skin/rabbit lethal dose (50 percent kill): 600 µL/kgUCDS** 12/15/1971

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 7 gm/kg/28D- continuousLung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Other changes
NTIS** OTS0559253

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWCHHSA* 9,6,2002

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 2 mg/m3, Skin, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 83852; Number of Industries 3; Total Number of Facilities 124; Number of Occupations 7; Total Number of Employees Exposed 6127; Total Number of Female Employees Exposed 119
National Occupational Hazard Survey 1974Hazard Code 83852; Number of Industries 5; Total Number of Facilities 126; Number of Occupations 11; Total Number of Employees Exposed 998

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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