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Registry of Toxic Effects of Chemical Substances (RTECS)

Propane, 1,3-bis(2,3-epoxypropoxy)-2,2-dimethyl-

RTECS #

TX3760000

CAS #

17557-23-2

Updated

October 1997

Molecular Weight

216.31

Molecular Formula

C11H20O4

Synonyms

1,3-Bis(2,3-epoxypropoxy)-2,2-dimethylpropane
2,2'-((2,2-Dimethyl-1,3-propanediyl)bis(oxymethylene))bisoxirane
Diglycidyl ether of neopentyl gylcol
Heloxy WC68
Neopentyl glycol diglycidyl ether
Oxirane, 2,2'-((2,2-dimethyl-1,3-propanediyl)bis(oxymethylene))bis- (9CI)

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium1 mg/plate (+/-enzymatic activation step)MUREAV 172,105,1986

Tumorigenic Data and References

Route/OrganismDoseEffectReference
skin/mouse lowest published toxic dose: 9393 mg/kg/2Y- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Skin and Appendages: Tumors
NTIS** ORNL-5762
skin/mouse toxic dose: 11 gm/kg/3Y- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Skin and Appendages: Tumors
NTIS** ORNL-5762
skin/mouse toxic dose: 17 gm/kg/2Y- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Skin and Appendages: Tumors
NTIS** ORNL-5762
skin/mouse toxic dose: 25 gm/kg/3Y- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Skin and Appendages: Tumors
NTIS** ORNL-5762

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lethal dose (50 percent kill): 4500 mg/kg38MKAJ 2A,2212,1981

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X1484; Number of Industries 6; Total Number of Facilities 77; Number of Occupations 7; Total Number of Employees Exposed 2838; Total Number of Female Employees Exposed 44

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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