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Registry of Toxic Effects of Chemical Substances (RTECS)

Potassium sulfate (2:1)

RTECS #

TT5900000

CAS #

7778-80-5; 10233-01-9

Updated

July 2013

Molecular Weight

174.26

Molecular Formula

O4S·2K

Synonyms

Sulfuric acid, dipotassium salt

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
In Vitro/Human, melanoma Inhibitor Concentration (50 percent kill): 7013.9 mg/L/48HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.FCTOD7 50,2084,2012
inhalation/mammal (species unspecified) lowest published toxic concentration: 60 mg/m3Lung, Thorax, or Respiration: Dyspnea

Lung, Thorax, or Respiration: Other changes
VCVN1* -,48,1998
intraperitoneal/guinea pig lowest published lethal dose: 3000 mg/kgBehavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory depression
VCVN1* -,48,1998
intraperitoneal/guinea pig lethal dose (50 percent kill): 1250 mg/kgVCVN1* -,48,1998
intraperitoneal/mouse lethal dose (50 percent kill): 1250 mg/kgVCVN1* -,48,1998
intraperitoneal/mouse lowest published lethal dose: 3000 mg/kgBehavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory depression
VCVN1* -,48,1998
intraperitoneal/rat lowest published lethal dose: 3000 mg/kgBehavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory depression
VCVN1* -,48,1998
intraperitoneal/rat lethal dose (50 percent kill): 1250 mg/kgVCVN1* -,48,1998
oral/guinea pig lethal dose (50 percent kill): 6600 mg/kgVCVN1* -,48,1998
oral/guinea pig lowest published lethal dose: 3000 mg/kgBehavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory depression
VCVN1* -,48,1998
oral/mouse lowest published lethal dose: 3000 mg/kgBehavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory depression
VCVN1* -,48,1998
oral/mouse lethal dose (50 percent kill): 6600 mg/kgVCVN1* -,48,1998
oral/rat lethal dose (50 percent kill): 6600 mg/kgVCVN1* -,48,1998
oral/rat lowest published lethal dose: 3000 mg/kgBehavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory depression
VCVN1* -,48,1998
oral/woman lowest published lethal dose: 750 mg/kgBehavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Other changes

Gastrointestinal: Hypermotility, diarrhea
AEXPBL 21,169,1886
subcutaneous/guinea pig lowest published lethal dose: 3 gm/kgHBAMAK 4,1360,1935

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 15 mg/m3/4H/17W- intermittentEndocrine: Changes in adrenal weight

Nutritional and Gross Metabolic: Changes in: Na

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
GTPZAB 28(7),47,1984
inhalation/rat lowest published toxic concentration: 15 mg/m3/4H/16W- intermittentLiver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in kidney weight

Immunological Including Allergic: Decreased immune response
VCVN1* -,48,1998

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWENTOX* -,110,2005

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 10 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X1826; Number of Industries 1; Total Number of Facilities 20; Number of Occupations 1; Total Number of Employees Exposed 238
National Occupational Exposure Survey 1983Hazard Code 60540; Number of Industries 62; Total Number of Facilities 6540; Number of Occupations 76; Total Number of Employees Exposed 120743; Total Number of Female Employees Exposed 31373
National Occupational Hazard Survey 1974Hazard Code 60540; Number of Industries 23; Total Number of Facilities 2504; Number of Occupations 40; Total Number of Employees Exposed 24082

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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