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Potassium pyrosulfite

RTECS #: TT4920000

CAS #: 16731-55-8


UPDATE: November 2007 MW: 222.32 MF: O5S2ĽK2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. REPRODUCTIVE EFFECTS DATA:
  4. REVIEWS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Dipotassium disulfite
  2. Dipotassium metabisulfite
  3. Disulfurous acid, dipotassium salt (9CI)
  1. Potassium metabisulfite
  2. Potassium disulfite
  3. Pyrosulfurous acid, dipotassium salt


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
unscheduled DNA synthesis oral
rat
400 mg/kg JJCREP 80,424,1989


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 35 gm/kg (49 day prior to copulation/1-21 day pregnant) Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) CRSBAW 172,470,1978


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 54,131,1992
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 54,131,1992
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMEMDT 54,131,1992
TOXICOLOGY REVIEW
IJTOFN 22,63,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 82177;
Number of Industries 17;
Total Number of Facilities 1,935;
Number of Occupations 13;
Total Number of Employees Exposed 5,348
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 82177;
Number of Industries 34;
Total Number of Facilities 4,265;
Number of Occupations 45;
Total Number of Employees Exposed 33,335;
Total Number of Female Employees Exposed 10,193


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA GENETOX PROGRAM 1988, Inconclusive: In vitro SCE-nonhuman
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE

CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849-
IJTOFN International Journal of Toxicology. (Taylor & Francis, 47 Runway Rd., Suite g, Levittown, PA 19057) V.16- 1997-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985-

Used as an industrial chemical, food and feed additive, flavor, packaging material

NIOSH PROFILE (PHOTOGRAPHIC PROCESSING), FIRL, 4/78

RTECS Compound Description:
   Tumorigen
   Mutagen
   Reproductive Effector

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