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Registry of Toxic Effects of Chemical Substances (RTECS)

Phthalic acid, diisooctyl ester

RTECS #

TI1300000

CAS #

27554-26-3; 1330-91-2

Updated

April 2012

Molecular Weight

390.62

Molecular Formula

C24H38O4

Synonyms

1,2-Benzenedicarboxylic acid, diisooctyl ester
Corflex 880
Diisooctyl phthalate
Flexol Plasticizer DIOP
Hexaplas M/O
Isooctyl phthalate
Phthalic acid, bis(6-methylheptyl)ester

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /rabbit 500 mg open irritation test mildUCDS** 6/11/1965

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/mouse lethal dose (50 percent kill): 2769 mg/kgGTPZAB 17(11),51,1973
oral/rat lethal dose (50 percent kill): 22 gm/kgEVHPAZ 3,61,1973
skin/rabbit lethal dose (50 percent kill): 12600 µL/kgUCDS** 6/11/1965

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-DENMARKtime-weighted average 3 mg/m3, MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 3 mg/m3, NOV2011
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 5 mg/m3, JAN2002
Occupational Exposure Limit-SWEDENtime-weighted average 3 mg/m3;short term exposure limit 5 mg/m3, JUN2005
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 5 mg/m3, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 83445; Number of Industries 3; Total Number of Facilities 387; Number of Occupations 5; Total Number of Employees Exposed 5416; Total Number of Female Employees Exposed 158
National Occupational Hazard Survey 1974Hazard Code 83445; Number of Industries 8; Total Number of Facilities 253; Number of Occupations 19; Total Number of Employees Exposed 4770

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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