Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Phosphorothioic acid, S-(2-(ethylthio)ethyl) O,O-dimethyl ester

RTECS #

TG1750000

CAS #

919-86-8

Updated

September 201

Molecular Weight

230.30

Molecular Formula

C6H15O3PS2

Synonyms

BAY 18436
Bayer 25/154
Demeton-S-methyl
Demeton-S-metile (Italian)
Dimethyl S-(2-eththioethyl)thiophosphate
Ethanethiol, 2-(ethylthio)-, S-ester with O,O-dimethyl phosphorothioate
Isometasystox
Metaisoseptox
Metaisosystox
Metasystox (I)
Metasystox forte
Metasystox J
Methyl demeton thioester
Methyl isosystox
Methyl thionodemeton
Methyl-mercaptofos teolery
O,O-Dimethyl 2-ethylmercaptoethyl thiophosphate, thiolo isomer
O,O-Dimethyl S-(2-(ethylthio)ethyl)phosphorothioate
O,O-Dimethyl S-(2-eththioethyl)phosphorothioate
O,O-Dimethyl S-ethylmercaptoethyl thiophosphate
O,O-Dimethyl-S-(2-aethylthio-aethyl)-monothiophosphat (German)
O,O-Dimethyl-S-(2-ethylthio-ethyl)-monothiofosfaat (Dutch)
O,O-Dimethyl-S-(3-thia-pentyl)-monothiophosphat (German)
O,O-Dimetil-S-(2-etiltio-etil)-monotiofosfato (Italian)
Phosphorothioic acid, O,O-dimethyl S-(2-(ethylthio)ethyl) ester
S-(2-(Ethylthio)ethyl) dimethyl phosphorothiolate
S-(2-(Ethylthio)ethyl) O,O-dimethyl phosphorothioate
S-(2-(Ethylthio)ethyl) O,O-dimethyl thiophosphate
Thiophosphate de O,O-dimethyle et de S-2-ethylthio-ethyle (French)

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium5 mg/plate (+enzymatic activation step)MUREAV 28,405,1975
mutation in microorganisms/Escherichia coli5 mg/plate (-enzymatic activation step)MUREAV 28,405,1975
sex chromosome loss and nondisjunctionoral/Drosophila melanogaster80 ppmMUREAV 28,405,1975

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): 500 mg/m3/4H85DPAN -,-,1971/1976
intraperitoneal/guinea pig lethal dose (50 percent kill): 12500 µg/kgTXAPA9 4,621,1962
intraperitoneal/rat lethal dose (50 percent kill): 7500 µg/kgTXAPA9 4,621,1962
intravenous/rat lethal dose (50 percent kill): 65 mg/kgBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other esterasesBIJOAK 67,187,1957
oral/guinea pig lethal dose (50 percent kill): 110 mg/kgTXAPA9 4,621,1962
oral/rat lethal dose (50 percent kill): 30 mg/kgFMCHA2 -,C197,1991
skin/rat lethal dose (50 percent kill): 85 mg/kgPHJOAV 185,361,1960
unreported route/mammal (species unspecified) lethal dose (50 percent kill): 40 mg/kg30ZDA9 -,346,1971

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.05 mg/m3 (inhal, vapor, skin)DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWDTTIAF 80,485,1973
TOXICOLOGY REVIEWRREVAH 63,1,1976

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-BELGIUMtime-weighted average 0.05 mg/m3 (vapor, aerosol), Skin, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.05 ppm (0.5 mg/m3), skin, MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.05 ppm (0.5 mg/m3), skin, NOV2011

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
TOP