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Registry of Toxic Effects of Chemical Substances (RTECS)

Phosphorodithioic acid, S-(chloromethyl) O,O-diethyl ester

RTECS #

TD5170000

CAS #

24934-91-6

Updated

March 2000

Molecular Weight

234.71

Molecular Formula

C5H12ClO2PS2

Synonyms

Chlormefos
Chlormephos
Dotan
MC 2188
S-(Chloromethyl) O,O-diethylphosphorodithioate
S-Chloromethyl-O,O-diethylphosphorothiolothionate

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): 88 mg/m3/4HEye: Other eye effects

Behavioral: Tremor

Kidney, Ureter, and Bladder: Incontinence
NTIS** OTS0571210
oral/chicken lethal dose (50 percent kill): 65 mg/kgNTIS** OTS0571931
oral/Dog lowest published lethal dose: 12500 µg/kgBehavioral: Ataxia

Gastrointestinal: Ulceration or bleeding from large intestine

Gastrointestinal: Nausea or vomiting
NTIS** OTS0570896
oral/guinea pig lethal dose (50 percent kill): 14 mg/kgNTIS** OTS0571931
oral/quail lethal dose (50 percent kill): 260 mg/kg85JFAN A081,1983
oral/rat lethal dose (50 percent kill): 7 mg/kgFMCHA2 -,C70,1991
skin/rabbit lethal dose (50 percent kill): >1600 mg/kgPEMNDP 9,148,1991
skin/rat lethal dose (50 percent kill): 27 mg/kgGUCHAZ 6,103,1973
subcutaneous/rat lethal dose (50 percent kill): 45 mg/kgEye: Lacrimation

Behavioral: Somnolence (general depressed activity)

Behavioral: Tremor
NTIS** OTS0571075

Status in Federal Agencies

OrganizationReference
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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