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Registry of Toxic Effects of Chemical Substances (RTECS)

Phosphoric acid, bis(2-ethylhexyl) ester

RTECS #

TB7875000

CAS #

298-07-7

Updated

April 2010

Molecular Weight

322.48

Molecular Formula

C16H35O4P

Synonyms

2-Ethyl-1-hexanol hydrogen phosphate
Bis(2-ethylhexyl)hydrogen phosphate
Bis(2-ethylhexyl)orthophosphoric acid
Bis(2-ethylhexyl)phosphate
Bis(2-ethylhexyl)phosphoric acid
Dehpa extractant
Di(2-ethylhexyl)orthophosphoric acid
Di(2-ethylhexyl)phosphate
Di-2(ethylhexyl)phosphoric acid
Hdehp
Kyselina di-(2-ethylhexyl)fosforecna (Czech)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 5 mg moderateUCDS** 5/18/1972
eye /rabbit 250 µg/24H severe85JCAE -,1130,1986
eye /rabbit 100 µL severeHPV341 -,-,2001
skin /rabbit 500 µL severeHPV341 -,-,2001
skin /rabbit 500 mg open irritation test moderateUCDS** 5/18/1972
skin /rabbit 5 mg/24H severe85JCAE -,1130,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lowest published lethal dose: 62500 µg/kgCBCCT* 9,132,1957
intraperitoneal/rabbit lethal dose (50 percent kill): 1250 mg/kgHPV341 -,-,2001
intraperitoneal/rat lethal dose (50 percent kill): 50 mg/kgHPV341 -,-,2001
intraperitoneal/rat lethal dose (50 percent kill): 50 mg/kgLiver: Other changesHYDRDA 3,201,1978
oral/rat lethal dose (50 percent kill): 4940 µL/kgUCDS** 5/18/1972
oral/rat lethal dose (50 percent kill): 4940 mg/kgHPV341 -,-,2001
skin/rabbit lethal dose (50 percent kill): 1250 µL/kgUCDS** 5/18/1972

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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